Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/865

Glucose tolerance tests and "in vivo" response to intravenous insulin in the unanaesthesized late pregnant rat and their consequences to the fetus.


Vista previa

Ver/Abrir:
 Glucose_Martin_et_al_Diab&Metab_1986.pdf
418,25 kB
Adobe PDF
Título : Glucose tolerance tests and "in vivo" response to intravenous insulin in the unanaesthesized late pregnant rat and their consequences to the fetus.
Autor : Martín, A.
Zorzano, Antonio
Caruncho, I.
Herrera Castillón, Emilio.
Materias: Pregnancy.Insulin resistance.Rat.Glucose.
Resumen : In the late pregnant rat, blood glucose levels were lower and plasma RIA-insulin levels were slightly higher than in virgin animals. Oral and intravenous glucose tolerance tests produced parallel changes in blood glucose in both groups whereas plasma RIA-insulin increased more in the pregnant animals. Blood glucose levels after either low (0.1-1 IU/Kg) or high (10 IU/Kg) doses of intravenous insulin decreased more slowly and less in pregnant than in virgin rats. Feta! blood glucose levels were not affected by maternal insulin treatment. Results show that in the unanaesthesized late pregnant rat both insulin sensitivity and responsiveness decreased and it is proposed that this insulin resistance may represent a mechanism to delay disposal of ingested nutrients by maternal tissues, ensuring their availability to the fetus.
Descripción : En: Diabete et metabolisme, ISSN 0338-1684, 1986. n. 12, p. 302-307
URI : http://hdl.handle.net/10637/865
Derechos: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
Fecha de publicación : 19-sep-1986
Centro : Universidad San Pablo-CEU
Aparece en las colecciones: Facultad de Farmacia





Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.