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http://hdl.handle.net/10637/15720Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution
| Title: | Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution |
| Authors : | Agudo Torres, Rubén Reetz, Manfred T. |
| Publisher: | Royal Society of Chemistry |
| Citation: | Agudo R, Reetz MT. Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution. Chem Commun (Camb). 2013 Dec 4;49(93):10914-6. doi: 10.1039/c3cc46229c. |
| Abstract: | Designer cells for a synthetic cascade reaction harnessing selective redox reactions were devised, featuring two successive regioselective P450-catalyzed CH-activating oxidations of 1-cyclohexene carboxylic acid methyl ester followed by stereoselective olefin-reduction catalysed by (R)- or (S)-selective mutants of an enoate reductase. |
| Description: | Acceso a la información de la publicación, a través de la siguiente URL: DOI https://doi.org/10.1039/C3CC46229C |
| URI: | http://hdl.handle.net/10637/15720 |
| Rights : | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
| ISSN: | 1364-548X |
| Issue Date: | 1-Oct-2013 |
| Center : | Universidad San Pablo-CEU |
| Appears in Collections: | Facultad de Farmacia |
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