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http://hdl.handle.net/10637/15720Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution
| Título : | Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution |
| Autor : | Agudo Torres, Rubén Reetz, Manfred T. |
| Editorial : | Royal Society of Chemistry |
| Citación : | Agudo R, Reetz MT. Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution. Chem Commun (Camb). 2013 Dec 4;49(93):10914-6. doi: 10.1039/c3cc46229c. |
| Resumen : | Designer cells for a synthetic cascade reaction harnessing selective redox reactions were devised, featuring two successive regioselective P450-catalyzed CH-activating oxidations of 1-cyclohexene carboxylic acid methyl ester followed by stereoselective olefin-reduction catalysed by (R)- or (S)-selective mutants of an enoate reductase. |
| Descripción : | Acceso a la información de la publicación, a través de la siguiente URL: DOI https://doi.org/10.1039/C3CC46229C |
| URI : | http://hdl.handle.net/10637/15720 |
| Derechos: | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
| ISSN : | 1364-548X |
| Fecha de publicación : | 1-oct-2013 |
| Centro : | Universidad San Pablo-CEU |
| Aparece en las colecciones: | Facultad de Farmacia |
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