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dc.creatorGalli, Verónica-
dc.creatorBarbas Arribas, Coral.-
dc.date2004-
dc.date.accessioned2011-09-19T15:40:10Z-
dc.date.available2011-09-19T15:40:10Z-
dc.date.issued2004-09-19T15:40:10Z-
dc.identifier000000450117-
dc.identifier.urihttp://hdl.handle.net/10637/1084-
dc.descriptionEn: Journal of chromatography A. ISSN 0021-9673, 2004. n. 1048 : 207-211 p.-
dc.description.abstractA method has been developed for the analysis of a cough syrup containing dextromethorphan, guaifenesin, benzoic acid, saccharin and other components. Forced degradation was also studied to demonstrate that the method could be employed during a stability study of the syrup. Final conditions were phosphate buffer (25 mM, pH 2.8) with triethylamine (TEA)–acetonitrile (75:25, v/v). In such conditions, all the actives, excipients and degradation products were baseline resolved in less than 14 min, and different wavelengths were used for the different analytes and related compounds.en-EN
dc.formatapplication/pdf-
dc.language.isoen-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es-
dc.subjectAnalysisen-EN
dc.subjectCough syrupen-EN
dc.subjectValidationen-EN
dc.subjectForced degradationen-EN
dc.titleHigh-performace liquid chromatographic analysis of dextromethorphan guaifenesin and benzoate in a cough syrup for stability testing.en-EN
dc.typeArtículo-
europeana.dataProviderUNIVERSIDAD SAN PABLO CEU-
europeana.isShownAthttp://hdl.handle.net/10637/1084-
europeana.objecthttp://repositorioinstitucional.ceu.es/visor/libros/450117/thumb_europeana/450117.jpg-
europeana.providerHispana-
europeana.rightshttp://creativecommons.org/publicdomain/zero/1.0/-
europeana.typeTEXT-
dc.centroUniversidad San Pablo-CEU-
Aparece en las colecciones: Facultad de Farmacia




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