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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.creator | Blázquez Fernández, Enrique | - |
dc.creator | Herrera Castillón, Emilio. | - |
dc.creator | Castro, Mario. | - |
dc.date | 1971 | - |
dc.date.accessioned | 2011-09-19T15:39:38Z | - |
dc.date.available | 2011-09-19T15:39:38Z | - |
dc.date.issued | 1971-09-19T15:39:38Z | - |
dc.identifier | 000000388204 | - |
dc.identifier.uri | http://hdl.handle.net/10637/1031 | - |
dc.description | En: Revista Española de Fisiología, ISSN 0034-9402 1971. N. 27, pp 297-304 | - |
dc.description.abstract | Male rats were fed a high-fat diet (B) and compared with age and sex paired controls fed a standard diet (A). After an 18 hr fast, the plasma levels of glucose and insulin were lower in B than in A and the oral glucose tolerance were less in the B group. Insulin release in vitro by the pancreas of the rats on the high-fat diet was lower than in the controls. The formation of glucose-C14 from alanine-C11 (IO-' M) by liver slices was higher and that of lactic acid-C14, pyruvic acid-C14 and C14O2 was lower in B vs A when the animals were fed. After a 48 hr fast the A group shows higher gluconeogenesis than when fed, while B remains at the fed rate, in such a way that the formation of glucose-C14 in A vs B is not different when the animals were fasted. The decreased pancreatic insulin release in B could result in such an activation of hepatic gluconeogenesis, that a further increase with fasting is no longer possible. | en_EN |
dc.format | application/pdf | - |
dc.language.iso | en | - |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | - |
dc.title | Effect of a high-fat diet on pancreatic insulin release, glucose tolerance and hepatic gluconeogenesis in male rats. | - |
dc.type | Artículo | - |
europeana.dataProvider | UNIVERSIDAD SAN PABLO CEU | - |
europeana.isShownAt | http://hdl.handle.net/10637/1031 | - |
europeana.object | http://repositorioinstitucional.ceu.es/visor/libros/388204/thumb_europeana/388204.jpg | - |
europeana.provider | Hispana | - |
europeana.rights | http://creativecommons.org/publicdomain/zero/1.0/ | - |
europeana.type | TEXT | - |
dc.centro | Universidad San Pablo-CEU | - |
Aparece en las colecciones: | Facultad de Farmacia |
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