Trull Ahuir, Carmen

The purpose of this study is to evaluate the efficiency of local platelet-rich plasma (PRP) injection as an adjuvant treatment after carpal ligament release. We conducted a prospective randomized, tripleblinded, controlled trial. Fifty participants with mild to extreme carpal tunnel syndrome (CTS) were randomly assigned either to the PRP (n = 25) or the platelet-poor plasma (PPP, n = 25) group. After performing open surgical release of the carpal ligament, the inside of the carpal tunnel was irrigated with 3 mL of PRP or PPP according to each participant’s group allocation. The primary outcome was hand grip strength (HGS). Secondary outcomes were the time taken off work after surgery (in days) and scores on the Wong–Baker Faces Scale, Boston Carpal Tunnel Questionnaire, and Southampton Wound Assessment Scale. We evaluated patients before treatment and at 6-weeks. As expected, the pain levels, symptom severity, and functional status improved in all the patients after surgery. However, intragroup analysis revealed that only the participants in the PRP group had regained their pre-operative HGS levels at 6-weeks follow-up. These findings indicate that PRP is an effective adjuvant treatment in patients with mild to severe CTS who require surgery.

Some studies have been conducted in Ethiopia to analyze the predictive factors associated with recovery or mortality in children with acute malnutrition, but no recent studies carried out in Oromia have analyze nutritional recovery status in this children. we studied the factors affecting nutritional recovery for survival in acutely malnourished children Southern Ethiopia. cohort study that included the children admitted to the (blinded for review) hospital (Oromia, Ethiopia) for acute malnutrition from January 2015 to December 2016 (n = 440). Kaplan–Meier tests and log-rank tests were used to describe the survival. Chi-squared tests and Spearman and Mann–Whitney U correlation tests were also employed. The mean survival time was shorter in children with severe versus moderate malnutrition at admission (49 days vs. 101 days; log-rank p = 0.042). The survival time was shorter in children with severe acute malnutrition at the time of admission. Survival time of children with moderate acute malnutrition was shorter in children who came from rural areas compared to urban areas. Severe acute malnutrition was associated with hospital stays, death rates, or transfer to another hospital. Practical implications: the results of this study may improve the care of children with malnutrition.