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http://hdl.handle.net/10637/5534Design and synthesis of simplified sordaricin derivatives as inhibitors of fungal protein synthesis
| Título : | Design and synthesis of simplified sordaricin derivatives as inhibitors of fungal protein synthesis |
| Autor : | Cuevas, Juan C. Martos, José L. Lavandera Díaz, José Luis |
| Materias: | Compuestos heterocíclicos.; Enzyme inhibitors.; Antibiotics.; Enzyme inhibitors.; Fungi.; Molecular.; Modelinglmechanics. |
| Resumen : | A reduction of the tetracyclic skeleton of sordarins and sordaricins to a cyclopentane ring bearing the pharmacophore functional groups led to new derivatives retaining part of their in vitro and whole-cell activity. |
| Descripción : | En: Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894x. n. 9, 1999, págs 103-108 |
| URI : | http://hdl.handle.net/10637/5534 |
| Derechos: | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
| Fecha de publicación : | 31-oct-1999 |
| Centro : | Universidad San Pablo-CEU |
| Aparece en las colecciones: | Medicina |
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