Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/15621
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.otherUniversidad San Pablo-CEU. Facultad de Farmacia-
dc.contributor.otherGrupo: Centro de metabolómica y bioanálisis (CEMBIO)-
dc.creatorCamunas-Alberca, Sandra M.-
dc.creatorMoran Garrido, María-
dc.creatorSáiz Galindo, Jorge-
dc.creatorVillaseñor Solis, Alma Cristina-
dc.creatorBarbas Arribas, Coral.-
dc.date.accessioned2024-03-19T17:46:13Z-
dc.date.available2024-03-19T17:46:13Z-
dc.date.issued2023-07-
dc.identifier.citationSandra M. Camunas-Alberca, Maria Moran-Garrido, Jorge Sáiz, Alma Villaseñor, Ameer Y. Taha, Coral Barbas, The role of oxylipins and their validation as biomarkers in the clinical context, TrAC Trends in Analytical Chemistry, Volume 164, 2023, 117065, ISSN 0165-9936, https://doi.org/10.1016/j.trac.2023.117065es_ES
dc.identifier.issn1879-3142-
dc.identifier.urihttp://hdl.handle.net/10637/15621-
dc.description.abstractOxylipins are bioactive lipid mediators that participate in a wide range of processes, from blood flow to inflammation. In recent years, their exhaustive characterization as potential biomarkers has been actively pursued. However, several analytical challenges and sources of variability, like the low abundance of oxylipins in samples, their structural diversity, and the lack of harmonized and validated protocols for sample selection, collection, storage, and preparation have hampered their translation into clinical settings. In this review, these sources of variability are addressed and are exemplified with their application in recent clinical studies in different diseases. Our overall analysis highlights the need to achieve harmonized protocols for generating reliable and reproducible results that could be integrated into clinical practice to reach their full diagnostic and prognostic potential.es_ES
dc.description.sponsorshipAcuerdo Transformativo – 2023-
dc.formatapplication/pdf-
dc.language.isoen-
dc.publisherElsevier-
dc.relation.ispartofTrAC Trends in Analytical Chemistry-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es-
dc.rightsOpen Access-
dc.subjectLC-MS/MS analysisen_EN
dc.subjectOxygenated fatty acidsen_EN
dc.subjectPUFAsen_EN
dc.subjectEicosanoidsen_EN
dc.subjectProstaglandinsen_EN
dc.subjectLeukotrienesen_EN
dc.subjectPro-resolving lipid mediatorsen_EN
dc.subjectBioactive lipid mediatorsen_EN
dc.titleThe role of oxylipins and their validation as biomarkers in the clinical contexten_EN
dc.typeArtículo-
dc.identifier.doi10.1016/j.trac.2023.117065-
dc.relation.projectIDMinistry of Science and Innovation of Spain (MICINN) and the European Regional Development Fund FEDER, grant number PID2021-122490NB-I00 a-
dc.relation.projectIDLa Caixa Foundation, grant number 01-09-2018-01-09-2020-
dc.centroUniversidad San Pablo-CEU-
Aparece en las colecciones: Facultad de Farmacia




Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.