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http://hdl.handle.net/10637/14605The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition
| Title: | The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition |
| Authors : | Girousse, Amandine Gil Ortega, Marta Bourlier, Virginie Juin, Noémie Casteilla, Loius Sengenès, Coralie |
| Keywords: | Ectopic adipocytes; Chemotaxis |
| Publisher: | Elsevier |
| Citation: | Amandine Girousse, Marta Gil-Ortega, Virginie Bourlier, Célia Bergeaud, Quentin Sastourné-Arrey, Cédric Moro, Corinne Barreau, Christophe Guissard, Julie Vion, Emmanuelle Arnaud, Jean-Philippe Pradère, Noémie Juin, Louis Casteilla, Coralie Sengenès, The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition, Cell Reports, Volume 27, Issue 2, 2019, Pages 323-333.e5, ISSN 2211-1247, https://doi.org/10.1016/j.celrep.2019.03.038. |
| Abstract: | Girousse et al. show that, in mice fed a high-fat diet, adipose stromal cells (ASCs) can egress subcutaneous adipose tissue and infiltrate skeletal muscle to form ectopic adipocytes, causing metabolic disturbance. ASC trafficking is regulated by the CXCR4/CXCL12 axis, and pioglitazone intermittent treatment can prevent muscle ectopic lipid deposition. |
| URI: | http://hdl.handle.net/10637/14605 |
| Rights : | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es OpenAccess |
| ISSN: | 2639-1856 |
| Issue Date: | 9-Apr-2019 |
| Center : | Universidad San Pablo-CEU |
| Appears in Collections: | Facultad de Farmacia |
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