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Impacts of resveratrol and pyrogallol on physicochemical, mechanical and biological properties of epoxy-resin sealers

Título : Impacts of resveratrol and pyrogallol on physicochemical, mechanical and biological properties of epoxy-resin sealers
Autor : Kharouf, Naji
Sauro, Salvatore.
Hardan, Louis
Fawzy, Amr
Suhanda, Ilona Eveline
Zghal, Jihed
Materias: Pyrogallol in Dentistry.Pyrogallol - Properties.Resveratrol - Propiedades.Resveratrol in Dentistry.Gums and resins, synthetic in Dentistry.Resveratrol - Aplicaciones en Odontología.Pirogalol - Propiedades.Gomas y resinas sintéticas - Aplicaciones en Odontología.Materiales dentales.Resveratrol - Properties.Dental materials.Pirogalol - Aplicaciones en Odontología.
Editorial : MDPI
Citación : Kharouf, N., Sauro, S., Hardan, L., Fawzi, A., Suhanda, I. E., Zghal, J., Addiego, F., Affolter-Zbaraszczuk, C., Arntz, Y., Ball, V., Meyer, F., Haikel, Y. & Mancino, D. (2022). Impacts of resveratrol and pyrogallol on physicochemical, mechanical and biological properties of epoxy-resin sealers. Bioengineering, vol. 9, i. 3 (22 feb.), art. 85. DOI: https://doi.org/10.3390/bioengineering9030085
Resumen : This study aimed at evaluating the physicochemical and biological properties of experimental epoxy-resin sealers containing polyphenols such as resveratrol and pyrogallol. A conventional epoxy resin (OB) was modified by adding different concentrations of resveratrol (RS) or pyrogallol (PY) to its composition. Antibacterial and antioxidant activities, mechanical properties, along with wettability and morphological changes were investigated. The results were statistically analyzed using ANOVA and multiple comparison tests ( = 0.05). The incorporation of the tested polyphenols into the epoxy resin enhanced its mechanical properties. PY demonstrated much better antioxidant and antibacterial activities than RS, which were associated with a higher release of PY. In contrast, PY showed a higher cytotoxicity than OB and OB doped with RS. OB containing PY presented a rougher surface and higher water absorption than OB doped with RS. Both tested polyphenols caused no notable changes to the overall porosity of OB. Resveratrol and pyrogallol may not only influence the morphology and mechanical properties of epoxy-resin sealers, but could also enhance antioxidant activity and antibacterial effects against Enterococcus faecalis. Most epoxy-resin sealers currently available in the market can be considered as “passive” materials. Thus, doping their composition with specific polyphenols may be a suitable strategy to confer some antibacterial properties, antioxidant potential, along with improvement of some mechanical properties.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2306-5354/9/3/85
Este artículo de investigación pertenece al número especial "Recent Advances in Biomaterials and Dental Disease".
En este artículo de investigación también participan: Frédéric Addiego, Christine Affolter-Zbaraszczuk, Youri Arntz, Vincent Ball, Florent Meyer, Youssef Haikel y Davide Mancino.
URI : http://hdl.handle.net/10637/14341
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2306-5354 (Electrónico)
Idioma: es
Fecha de publicación : 22-feb-2022
Centro : Universidad Cardenal Herrera-CEU
Aparece en las colecciones: Dpto. Odontología





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