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Título : A review of current knowledge of myeloproliferative disorders in the horse
Autor : Satué Ambrojo, Katiuska.
Gardon Poggi, Juan Carlos.
Muñoz Juzado, Ana.
Materias: Cáncer en los caballos.Cancer in horses.Veterinary hematology.Caballos - Hematología.Veterinary oncology.Caballos - Enfermedades.Horses - Diseases.Hematología veterinaria.Oncología veterinaria.Horses - Hematology.
Fecha de publicación : 23-feb-2021
Editorial : BioMed Central.
Citación : Satué, K., Gardon, J.C. & Muñoz, A. (2021). A review of current knowledge of myeloproliferative disorders in the horse. Acta Veterinaria Scandinavica, vol. 63, art. 8 (23 feb.). DOI: https://doi.org/10.1186/s13028-021-00573-3
Resumen : Myeloid disorders are conditions being characterized by abnormal proliferation and development of myeloid lineage including granulocytes (neutrophils, eosinophils and basophils), monocytes, erythroids, and megakaryocytes precursor cells. Myeloid leukemia, based on clinical presentation and proliferative rate of neoplastic cells, is divided into acute (AML) and myeloproliferative neoplasms (MPN). The most commonly myeloid leukemia reported in horses are AML-M4 (myelomonocytic) and AML-M5 (monocytic). Isolated cases of AML-M6B (acute erythroid leukemia), and chronic granulocytic leukemia have also been reported. Additionally, bone marrow disorders with dysplastic alterations and ineffective hematopoiesis affecting single or multiple cell lineages or myelodysplastic diseases (MDS), have also been reported in horses. MDSs have increased myeloblasts numbers in blood or bone marrow, although less than 20%, which is the minimum level required for diagnosis of AML. This review performed a detailed description of the current state of knowlegde of the myeloproliferative disorders in horses following the criteria established by the World Health Organization.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://actavetscand.biomedcentral.com/track/pdf/10.1186/s13028-021-00573-3.pdf
URI : http://hdl.handle.net/10637/12881
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 1751-0147 (Electrónico).
Aparece en las colecciones: Dpto. Medicina y Cirugía Animal

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