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Genotyping and molecular characterization of antimicrobial resistance in thermophilic "Campylobacter" isolated from poultry breeders and their progeny in Eastern Spain


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Title: Genotyping and molecular characterization of antimicrobial resistance in thermophilic "Campylobacter" isolated from poultry breeders and their progeny in Eastern Spain
Authors : Marín Orenga, Clara
Sevilla Navarro, Sandra
Lonjedo, R.
Catalá Gregori, Pablo
Ferrús Pérez, María Antonia
Vega García, Santiago
Jiménez Belenguer, Ana Isabel
Keywords: Vibriosis - Spain - Valencia (Autonomous Community).Vibriosis - España - Comunidad Valenciana.Aves de corral - Enfermedades infecciosas - España - Comunidad Valenciana.Bacterias - Resistencia a los medicamentos.Bacterias Gram-Negativas - España - Comunidad Valenciana.Drug resistance in microorganisms.Poultry - Communicable diseases - Spain - Valencia (Autonomous Community).Gram-Negative Bacteria - Spain - Valencia (Autonomous Community).
Publisher: Elsevier
Citation: Marin, C., Sevilla-Navarro, S., Lonjedo, R., Catalá-Gregori, P., Ferrús, M.A., Vega, S. et al. (2020). Genotyping and molecular characterization of antimicrobial resistance in thermophilic "Campylobacter" isolated from poultry breeders and their progeny in Eastern Spain. Poultry Science, vol. 99, n. 10 (01 oct.), pp. 5096-5104. DOI: https://doi.org/10.1016/j.psj.2020.06.043
Abstract: Thermophilic Campylobacter spp. are recognized as a major cause of acute bacterial diarrhea in humans, with broiler meat being the most common source of human infection. Antibiotic therapy is usually necessary for severe or prolonged infections, especially in immunocompromised populations such as young or elderly individuals. However, different studies have demonstrated a close association between antibiotic use in animal production and antimicrobial resistance (AMR) in humans. In this sense, there is social pressure to reduce antibiotic administration and find adequate alternatives to control the presence of bacterial infections in farms. However, there is a lack of information related to Campylobacter AMR dynamics through the entire production system from breeders to their progeny. It is unknown if resistance genes are a result of adaptation through chromosomal mutation or through horizontal gene transfer, instead of vertical transmission of DNA from the parent to their progeny. Thus, the main objectives of this study were to assess the main AMR rates present in a poultry production system, to study the relationship between Campylobacter AMR profiles from breeders and their progeny, and to study the presence and distribution of antibiotic resistance genes in poultry production. Regarding AMR rates, ciprofloxacin was classified as extremely high, followed by nalidixic acid and tetracyclines that were classified as very high. Moreover, this study demonstrated a relationship between theAMR patterns and genes found from Campylobacter strains isolated in breeders and those present in their progeny.
Description: Este artículo se encuentra disponible en la siguiente URL: https://www.sciencedirect.com/science/article/pii/S0032579120304089
En este artículo de investigación también participan: A. Jiménez-Belenguer.
URI: http://hdl.handle.net/10637/12742
Rights : http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
ISSN: 0032-5791
1525-3171 (Electrónico).
Issue Date: 1-Oct-2020
Center : Universidad Cardenal Herrera-CEU
Appears in Collections:Dpto. Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos





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