Please use this identifier to cite or link to this item: http://hdl.handle.net/10637/10504

Physicochemical and microbiological assessment of an experimental composite doped with Triclosan-Loaded Halloysite Nanotubes

Title: Physicochemical and microbiological assessment of an experimental composite doped with Triclosan-Loaded Halloysite Nanotubes
Authors : Cunha, Diana A.
Rodrigues, Nara S.
Souza, Lidiane C.
Lomonaco, Diego
Rodrigues, Flávia P.
Degrazia, Felipe Weidenbach
Collares, Fabrício M.
Sauro, Salvatore.
Saboia, Vicente P.A.
Keywords: Gomas y resinas - Aplicaciones en Odontología.Bactericidas.Adhesivos dentales.Dental adhesives.Dentistry, Operative.Germicides.Triclosán - Uso terapéutico.Cementos dentales.Materiales dentales.Dental materials.Triclosan - Therapeutic use.Dental cements.Microbiología industrial.Industrial microbiology.Odontología restauradora.Gums and resins in Dentistry.
Publisher: MDPI
Citation: Cunha, Diana A., Rodrigues, Nara S., Souza, Lidiane C., Lomonaco, Diego, Rodrigues, Flávia P., Degrazia, Felipe W., Collares, Fabrício M., Sauro, Salvatore and Saboia, Vicente P.A. (2018). Physicochemical and Microbiological Assessment of an Experimental Composite Doped with Triclosan-Loaded Halloysite Nanotubes. Materials, vol. 11, no. 7, art. 1080. DOI: https://doi.org/10.3390/ma11071080
Abstract: This study is aimed at evaluating the effects of triclosan-encapsulated halloysite nanotubes (HNT/TCN) on the physicochemical and microbiological properties of an experimental dental composite. A resin composite doped with HNT/TCN (8% w/w), a control resin composite without nanotubes (HNT/TCN-0%) and a commercial nanofilled resin (CN) were assessed for degree of conversion (DC), flexural strength (FS), flexural modulus (FM), polymerization stress (PS), dynamic thermomechanical (DMA) and thermogravimetric analysis (TGA). The antibacterial properties (M) were also evaluated using a 5-day biofilm assay (CFU/mL). Data was submitted to one-way ANOVA and Tukey tests. There was no significant statistical difference in DC, FM and RU between the tested composites (p > 0.05). The FS and CN values attained with the HNT/TCN composite were higher (p < 0.05) than those obtained with the HNT/TCN-0%. The DMA analysis showed significant differences in the TAN (p = 0.006) and Tg (p = 0) between the groups. TGA curves showed significant differences between the groups in terms of degradation (p = 0.046) and weight loss (p = 0.317). The addition of HNT/TCN induced higher PS, although no significant antimicrobial effect was observed (p = 0.977) between the groups for CFUs and (p = 0.557) dry weight. The incorporation of HNT/TCN showed improvements in physicochemical and mechanical properties of resin composites. Such material may represent an alternative choice for therapeutic restorative treatments, although no significance was found in terms of antibacterial properties. However, it is possible that current antibacterial tests, as the one used in this laboratory study, may not be totally appropriate for the evaluation of resin composites, unless accompanied with aging protocols (e.g., thermocycling and load cycling) that allow the release of therapeutic agents incorporated in such materials.
Description: Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.mdpi.com/1996-1944/11/7/1080
URI: http://hdl.handle.net/10637/10504
Rights : http://creativecommons.org/licenses/by/4.0/deed.es
ISSN: 1996-1944.
Issue Date: 1-Jul-2018
Center : Universidad Cardenal Herrera-CEU
Appears in Collections:Dpto. Odontología





Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.