Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution
dc.centro | Universidad San Pablo-CEU | |
dc.contributor.author | Reetz, Manfred T. | |
dc.contributor.author | Agudo Torres, Rubén | |
dc.contributor.other | Universidad San Pablo-CEU. Departamento de Ciencias Farmacéuticas y de la Salud | |
dc.contributor.other | Grupo: Parasitología e Inmunología molecular con aplicación biotecnológica, diagnóstica y terapéutica (PARINM) | |
dc.date.accessioned | 2024-04-10T14:50:16Z | |
dc.date.available | 2024-04-10T14:50:16Z | |
dc.date.issued | 2013-10-01 | |
dc.description | Acceso a la información de la publicación, a través de la siguiente URL: DOI https://doi.org/10.1039/C3CC46229C | |
dc.description.abstract | Designer cells for a synthetic cascade reaction harnessing selective redox reactions were devised, featuring two successive regioselective P450-catalyzed CH-activating oxidations of 1-cyclohexene carboxylic acid methyl ester followed by stereoselective olefin-reduction catalysed by (R)- or (S)-selective mutants of an enoate reductase. | en_EN |
dc.identifier.citation | Agudo R, Reetz MT. Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution. Chem Commun (Camb). 2013 Dec 4;49(93):10914-6. doi: 10.1039/c3cc46229c. | |
dc.identifier.doi | 10.1039/C3CC46229C | |
dc.identifier.issn | 1364-548X | |
dc.identifier.uri | http://hdl.handle.net/10637/15720 | |
dc.language.iso | en | |
dc.publisher | Royal Society of Chemistry | en_EN |
dc.relation.ispartof | Chemical Communications | |
dc.rights | metadata only access | |
dc.rights.cc | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.title | Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution | en_EN |
dc.type | Artículo | |
dspace.entity.type | Publication | es |
relation.isAuthorOfPublication | 6c8d28e1-0f33-443a-a16b-508aef52ff02 | |
relation.isAuthorOfPublication.latestForDiscovery | 6c8d28e1-0f33-443a-a16b-508aef52ff02 |
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