Capillary electrophoresis of glutathione to monitor oxidative stress and response to antioxidant treatments in an animal model.

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dc.centroUniversidad San Pablo-CEU
dc.contributor.authorMaeso Nava, Nuria
dc.contributor.authorBarbas Arribas, Coral
dc.contributor.authorGarcía Martínez, Diana
dc.contributor.authorRupérez Pascualena, Francisco Javier
dc.contributor.authorCifuentes, Alejandro
dc.date2005-
dc.date.accessioned2011-09-19T15:40:05Z
dc.date.available2011-09-19T15:40:05Z
dc.date.issued2005-09-19T15:40:05Z
dc.descriptionEn: Journal of chromatography B. 2005. vol. 822, n. 1-2 : 61-69 p. 0378-4348-
dc.descriptionArtículo en colaboración con: D. García-Martínez, F.J. Ruperez, A. Cifuentes, C. Barbases-ES
dc.description.abstractGlutathione plays a central role in metabolism and antioxidant defence. Several factors can influence the analytical efficiency and rapidity of the quantitative determination of glutathione. Procedures in sample pre-treatment have been compared in order to minimize analytical errors. Capillary electrophoresis has been chosen as a more adequate technique for obtaining a rapid and simple method for glutathione and glutathione disulfide determination in the blood and liver of the rat. The methods, once optimised, have been validated and applied for monitoring the oxidative stress in an animal model, such as the rat made diabetic by streptozotocin injection, when the animals are treated with antioxidants and compared with the corresponding controls.en-EN
dc.formatapplication/pdf-
dc.identifier000000402463-
dc.identifier.urihttp://hdl.handle.net/10637/835
dc.language.isoen-
dc.rights.cchttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.rights.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subjectGlutathione.en-EN
dc.subjectAntioxidants.en-EN
dc.subjectOxidative stress.en-EN
dc.subjectRat.en-EN
dc.subjectBlood.en-EN
dc.subjectLiver.en-EN
dc.subjectIn vivo assay.en-EN
dc.titleCapillary electrophoresis of glutathione to monitor oxidative stress and response to antioxidant treatments in an animal model.-
dc.typeArtículo-
dspace.entity.typePublicationes
europeana.dataProviderUNIVERSIDAD SAN PABLO CEU
europeana.isShownAthttp://hdl.handle.net/10637/835
europeana.objecthttp://repositorioinstitucional.ceu.es/visor/libros/402463/thumb_europeana/402463.jpg
europeana.providerHispana
europeana.rightshttp://creativecommons.org/publicdomain/zero/1.0/
europeana.typeTEXT
relation.isAuthorOfPublicatione8403ac2-8b40-4d56-aa05-eda90d8a60cf
relation.isAuthorOfPublication55a5c496-461e-4e9b-865f-420c4166fa26
relation.isAuthorOfPublication.latestForDiscoverye8403ac2-8b40-4d56-aa05-eda90d8a60cf

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