Please use this identifier to cite or link to this item: http://hdl.handle.net/10637/703

Chiral analysis of aliphatic short chain organic acids by capillary electrophoresis.

Title: Chiral analysis of aliphatic short chain organic acids by capillary electrophoresis.
Authors : Saavedra, Luis
Barbas Arribas, Coral.
Keywords: Anions.Organic acids.Carboxylic acids.Cyclodextrins.Enantiomers.Capillary electrophoresis.
Abstract: Short chain organic acids play an important role in different areas such as biochemistry, clinical chemistry, or the food industry. The enantiomeric ratio of chiral metabolites is an important parameter for the understanding of metabolic processes and in many cases it can serve diagnostic purposes. On the other hand, the presence of racemates in food products could indicate the use of organic acids as additives; this is not always permitted and needs to be controlled. The short chain of these acids makes difficult the three point interaction generally accepted as necessary for chiral recognition. Relatively recent publications have demonstrated the feasibility of their direct chiral separation in capillary electrophoresis by various techniques utilizing exchange capillary electrophoresis, macrocyclic antibiotics, cyclodextrins, ion-pair method, and transition metal complexes. The present article describes existing methods and strategies proposed to advance these areas.
Description: En: Journal of separation science. ISSN 1615-9306. n. 25 (2002), p. 1190-1196
URI: http://hdl.handle.net/10637/703
Rights : http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
Issue Date: 19-Sep-2001
Center : Universidad San Pablo-CEU
Appears in Collections:Facultad de Farmacia





Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.