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http://hdl.handle.net/10637/5540First pharmacophoric hypothesis for 5-HT7 antagonism
| Title: | First pharmacophoric hypothesis for 5-HT7 antagonism |
| Authors : | López Rodríguez, María L. Porras, Esther Benhamú, Bellinda Ramos, José A. Morcillo, M. José Lavandera Díaz, José Luis |
| Keywords: | Compuestos heterocíclicos. |
| Abstract: | In order to make the rst contribution to the elucidation of essential structural features for 5-HT7 antagonism, a set of thirty 5-HT7 antagonists were selected from the literature. A pharmacophore model was built using Molecular Modeling studies with Catalyst program. The information contained in this model was validated with new synthesized compounds. |
| Description: | En: Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894x. v. 10, 2000, págs 1097-1100 |
| URI: | http://hdl.handle.net/10637/5540 |
| Rights : | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
| Issue Date: | 1-Nov-2000 |
| Center : | Universidad San Pablo-CEU |
| Appears in Collections: | Medicina |
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