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http://hdl.handle.net/10637/5534Design and synthesis of simplified sordaricin derivatives as inhibitors of fungal protein synthesis
| Title: | Design and synthesis of simplified sordaricin derivatives as inhibitors of fungal protein synthesis |
| Authors : | Cuevas, Juan C. Martos, José L. Lavandera Díaz, José Luis |
| Keywords: | Compuestos heterocíclicos.; Enzyme inhibitors.; Antibiotics.; Enzyme inhibitors.; Fungi.; Molecular.; Modelinglmechanics. |
| Abstract: | A reduction of the tetracyclic skeleton of sordarins and sordaricins to a cyclopentane ring bearing the pharmacophore functional groups led to new derivatives retaining part of their in vitro and whole-cell activity. |
| Description: | En: Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894x. n. 9, 1999, págs 103-108 |
| URI: | http://hdl.handle.net/10637/5534 |
| Rights : | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
| Issue Date: | 31-Oct-1999 |
| Center : | Universidad San Pablo-CEU |
| Appears in Collections: | Medicina |
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