Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/14204
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.otherUniversidad San Pablo-CEU. Facultad de Farmacia. Departamento de Química y Bioquímica-
dc.creatorMoran Garrido, María-
dc.creatorCamunas-Alberca, Sandra M.-
dc.creatorGil de la Fuente, Alberto-
dc.creatorMariscal Jiménez, Antonio-
dc.creatorGradillas Nicolás, Ana-
dc.creatorBarbas Arribas, Coral.-
dc.creatorSáiz Galindo, Jorge-
dc.date2022-
dc.date.accessioned2023-04-21T04:00:34Z-
dc.date.available2023-04-21T04:00:34Z-
dc.date.issued2022-06-02-
dc.identifier000000737913-
dc.identifier.citationMoran-Garrido, M., Camunas-Alberca, S. M., Gil-de-la Fuente, A., Mariscal, A., Gradillas, A., Barbas, C., & Sáiz, J. (2022). Recent developments in data acquisition, treatment and analysis with ion mobility-mass spectrometry for lipidomics. Proteomics, 22, e2100328. https://doi.org/10.1002/pmic.202100328-
dc.identifier.issn1615-9861-
dc.identifier.urihttp://hdl.handle.net/10637/14204-
dc.description.abstractLipids are involved in many biological processes and their study is constantly increasing. To identify a lipid among thousand requires of reliablemethods and techniques. Ion Mobility (IM) can be coupled with Mass Spectrometry (MS) to increase analytical selectivity in lipid analysis of lipids. IM-MS has experienced an enormous development in several aspects, including instrumentation, sensitivity, amount of information collected and lipid identification capabilities. This review summarizes the latest developments in IM-MS analyses for lipidomics and focuses on the current acquisition modes in IM-MS, the approaches for the pre-treatment of the acquired data and the subsequent data analysis.Methods and tools for the calculation of Collision Cross Section (CCS) values of analytes are also reviewed. CCS values are commonly studied to support the identification of lipids, providing a quasi-orthogonal property that increases the confidence level in the annotation of compounds and can be matched in CCS databases. The information contained in this review might be of help to new users of IM-MS to decide the adequate instrumentation and software to perform IM-MS experiments for lipid analyses, but also for other experienced researchers that can reconsider their routines and protocols.en_EN
dc.description.sponsorshipAcuerdo Transformativo - 2022-
dc.formatapplication/pdf-
dc.language.isoen-
dc.publisherWiley-
dc.relation.ispartofProteomics-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es-
dc.rightsopenAccess-
dc.subjectAcquisitionen_EN
dc.subjectDataen_EN
dc.subjectDatabasesen_EN
dc.subjectIon mobilityen_EN
dc.subjectLipidomicsen_EN
dc.subjectMass spectrometryen_EN
dc.titleRecent developments in data acquisition, treatment and analysis with ion mobility-mass spectrometry for lipidomics-
dc.typeArtículo-
dc.identifier.doi10.1002/pmic.202100328-
dc.centroUniversidad San Pablo-CEU-
Aparece en las colecciones: Facultad de Farmacia




Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.