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Feline polycystic kidney disease : an update


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Título : Feline polycystic kidney disease : an update
Autor : Schirrer, Lorie
Marín García, Pablo Jesús
Llobat Bordes, Lola
Materias: Cats - Genetic disorders - Diagnosis.Gatos - Aparato urinario - Enfermedades - Diagnóstico.Gatos - Enfermedades genéticas - Diagnóstico.Cats - Urinary organs - Diseases - Diagnosis.
Editorial : MDPI
Citación : Schirrer, L., Marín-García, P. J. & Llobat, L. (2021). Feline polycystic kidney disease: an update. Veterinary Sciences, vol. 8, i. 11 (08 nov.), art. 269. DOI: https://doi.org/10.3390/vetsci8110269
Resumen : Polycystic kidney disease (PKD) is a disease that affects felines and other mammals, such as humans. The common name is autosomal dominant polycystic kidney disease (ADPKD) and causes a progressive development of fluid-filled cysts in the kidney and sometimes in other organs as the liver and pancreas. The formation and growth of cysts progress slowly, causing deterioration of kidney tissue and a gradual decrease in kidney function, leading to irreversible kidney failure. Feline PKD or ADPKD in humans are hereditary pathologies of autosomal dominant transmission. ADPKD is one of the genetic diseases with the highest prevalence in humans. In cats, this disease also has a high prevalence, mainly in the Persian breed, being one of the most common feline genetic diseases. Imaging tests seem to be the most reliable method for diagnosis of the disease, although more genetic tests are being developed to detect the presence of the responsible mutation. In this review, we summarize the current knowledge about feline PKD to guide future research related to an adequate diagnosis and early detection of causal mutations. It can allow the establishment of selection programs to reduce or eliminate this pathology in feline breeds.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2306-7381/8/11/269
URI : http://hdl.handle.net/10637/13447
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2306-7381
Fecha de publicación : 8-nov-2021
Centro : Universidad Cardenal Herrera-CEU
Aparece en las colecciones: Dpto. Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos





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