Please use this identifier to cite or link to this item: http://hdl.handle.net/10637/1055

Morphological and compositional changes of rat plasma triglyceride-rich lipoproteins incubated with adipose tissue.

Title: Morphological and compositional changes of rat plasma triglyceride-rich lipoproteins incubated with adipose tissue.
Authors : Lasunción, Miguel Ángel.
Herrera Castillón, Emilio.
Llobera i Sande, Miquel
Abstract: Triglyceride-rich rat lipoproteins (mainly VLDL), purified by ultracentrifugation and dialysis, were incubated for 120 min in the presence of epididymal fat-pad pieces from fed rats in media containing heparin. During this process, the lipoproteins were depleted of triglycerides and proportionally enriched with proteins, causing their increased density. After incubation, electron microscopic study of the triglyceride- rich lipoproteins revealed partially degraded structures, and some particles had atypical discoid flattened form and marked lamellar structure. These findings are in agreement with those of BLANCHETTE-MACKIE & Scow (l 976) in triglyceride hydrolysed chylomicrons and confirm their observation of monolayers formed by accumulated lipolytic products that move by lateral diffusion, giving rise to a spiral fold between the core triglycerides and the aqueous space.
Description: En: Archives Internacionales de Physiologie et de Biochimie, ISSN 0003-9799, n. 89, 1981, p. 57-62
URI: http://hdl.handle.net/10637/1055
Rights : http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
Issue Date: 19-Sep-1981
Center : Universidad San Pablo-CEU
Appears in Collections:Facultad de Farmacia





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