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http://hdl.handle.net/10637/10223Anti-angiogenic drug loaded liposomes : nanotherapy for early atherosclerotic lesions in mice
| Title: | Anti-angiogenic drug loaded liposomes : nanotherapy for early atherosclerotic lesions in mice |
| Authors : | Pont, Isabel Calatayud Pascual, María Aracely López Castellano, Alicia Cristina Albelda Gimeno, Elena Patricia García España, Enrique Martí Bonmatí, Luis Frías Martínez, Juan Carlos Albelda, M. Teresa |
| Keywords: | Arteriosclerosis - Chemotherapy.; Arterias - Enfermedades - Tratamiento.; Fumagilina - Uso terapéutico.; Ateroesclerosis - Farmacoterapia.; Fumagillin - Therapeutic use.; Arteriosclerosis - Farmacoterapia.; Liposomas.; Arteries - Diseases - Treatment.; Liposomes.; Atherosclerosis - Chemotherapy. |
| Publisher: | PLOS. |
| Citation: | Pont, I, Calatayud Pascual, A., López Castellano, A. Albedlda, EP., García España, E. Martí Bonmatí, L. et al. (2018). Anti-angiogenic drug loaded liposomes : nanotherapy for early atherosclerotic lesions in mice. PLoS ONE, vol. 13 (january), n. 1, art. e0190540. DOI: https://doi.org/10.1371/journal.pone.0190540 |
| Abstract: | Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment. |
| Description: | Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190540 También participan en la elaboración de este artículo científico: Aracely Calatayud-Pascual, Alicia López-Castellano, Elena P. Albelda, Enrique García-España, Luis Martí-Bonmatí, Juan C. Frias y M. Teresa Albelda. |
| URI: | http://hdl.handle.net/10637/10223 |
| Rights : | http://creativecommons.org/licenses/by/4.0/deed.es |
| ISSN: | 1932-6203. |
| Issue Date: | 1-Jan-2018 |
| Center : | Universidad Cardenal Herrera-CEU |
| Appears in Collections: | Dpto. Farmacia |
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