Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10637/16143
Pathological spectrum of ovine pulmonary adenocarcinoma in small ruminants: a focus on the mixed form
![no-thumbnail](/image/nothumb.jpg)
Título : | Pathological spectrum of ovine pulmonary adenocarcinoma in small ruminants: a focus on the mixed form |
Autor : | Ortega Porcel, Joaquín Corpa Arenas, Juan Manuel Castillo, Diego Murphy, Brian G. |
Materias: | Ovejas; Sheep; Enfermedad animal; Animal diseases; Cáncer; Cancer; Aparato respiratorio; Respiratory systems |
Editorial : | MDPI |
Citación : | Ortega J, Corpa JM, Castillo D, Murphy BG. Pathological spectrum of ovine pulmonary adenocarcinoma in small ruminants: a focus on the mixed form. Animals, vol. 13, i. 18 (06 sep.), art. 2828. DOI: https://doi.org/10.3390/ani13182828 |
Resumen : | Ovine pulmonary adenocarcinoma (OPA) is a contagious respiratory tumor of small ruminants, manifesting in chronic weight loss and respiratory failure. Infection with the betaretrovirus jaagsiekte sheep retrovirus (JSRV) is the cause of OPA. Here, we describe the gross and microscopic features of twenty-six sheep and one goat with naturally occurring JSRV-associated OPA. All the animals included in this study had pulmonary lesions morphologically consistent with OPA, but the majority of the observed lesions demonstrated features of both the classical and the atypical form of OPA, and were, therefore, classified grossly as mixed. The gross lesions were located mainly in the cranial pulmonary lobes, were multifocal to coalescing, variable in number and size, flat to slightly raised, firm, and white to grey. Histologically, the cases were classified according to the predominant architectural patterns as lepidic, papillary, acinar, or mixed; the mixed histological pattern was the most prevalent. The aim of this study was to describe the gross and microscopic spectrum of OPA in naturally infected small ruminants from Spain. The mixed form of OPA is less commonly reported, and can be confused with other concurrent pulmonary pathologies (such as BALT hyperplasia in SRLV-associated pneumonia or lungworm granulomas). |
URI : | http://hdl.handle.net/10637/16143 |
Derechos: | http://creativecommons.org/licenses/by/4.0/deed.es Open Access |
ISSN : | 2076-2615 (Electrónico) |
Fecha de publicación : | 6-sep-2023 |
Centro : | Universidad Cardenal Herrera-CEU |
Aparece en las colecciones: | Dpto. Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos |
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.