Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/12541
Título : Curcumin as a therapeutic option in retinal diseases
Autor : López Malo, Daniel.
Villarón Casares, Carlos Alberto.
Alarcón Jiménez, Jorge.
Miranda Sanz, María.
Díaz Llopis, Manuel.
Romero Gómez, Francisco Javier.
Villar Amigó, Vicente.
Materias: Oxidative stress.Curcumin - Therapeutic use.Estrés oxidativo.Retina - Enfermedades - Tratamiento.Retina - Diseases - Treatment.Curcumina - Uso terapéutico.
Fecha de publicación : 6-ene-2020
Editorial : MDPI
Citación : López-Malo, D., Villarón-Casares, C.A., Alarcón-Jiménez, J., Miranda, M., Díaz-Llopis, M., Romero, F.J., et al. (2020). Curcumin as a therapeutic option in retinal diseases. Antioxidants, vol. 9, i. 1 (06 jan.), art. 48. DOI: https://doi.org/10.3390/antiox9010048
Resumen : The retina is subjected to oxidative stress due to its high vascularization, long time light exposition and a high density of mitochondria. Oxidative stress can lead to pathological processes, like cell apoptosis, angiogenesis and inflammation ending in retinal pathologies. Curcumin, a major bioactive component obtained from the spice turmeric (Curcuma longa) rhizome has been used for centuries in Asian countries for cooking and for curing all kinds of diseases like dysentery, chest congestion and pain in general, due to its antioxidant e ects. Curcumin prevents the formation of reactive oxygen species and so it is a good protective agent. Curcumin has shown also anti-inflammatory, and antitumor properties. Curcumin is a natural product, which can be a therapeutic option in a variety of retinal diseases due to its pleiotropic properties. Some drawbacks are its poor solubility, bioavailability and lack of stability at physiological conditions; which have been shown in curcumin skeptical publications. In this review, we provide some lights and shadows on curcumin administration on the major retinal pathologies.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2076-3921/9/1/48
Este artículo pertenece al número especial "Natural products in health promotion and disease prevention".
En este artículo también participa: Vincent M. Villar.
URI : http://hdl.handle.net/10637/12541
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2076-3921 (Electrónico).
Aparece en las colecciones: Dpto. Ciencias Biomédicas

Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Curcumin_Lopez_ANTIOXIDANTS_2020.pdf923,26 kBAdobe PDFVisualizar/Abrir



Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.