Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/12487
Título : Relationship between Vitamin B12 and cobalt metabolism in domestic ruminant : an update
Autor : González Montaña, José Ramiro.
Escalera Valente, Francisco.
Alonso Díez, Ángel Javier.
Lomillos Pérez, Juan Manuel.
Robles, Roberto.
Alonso de la Varga, Marta Elena.
Materias: Avitaminosis.Cobalto.Vitamina B12.Cobalt.Ganado vacuno lechero - Alimentación.Dairy cattle - Feeding and feeds.Vitamin B12.
Fecha de publicación : 12-oct-2020
Editorial : MDPI
Citación : González-Montaña, J.R., Escalera-Valente, F., Alonso, A.J., Lomillos, J.M., Robles, R. & Alonso, M.E. (2020). Relationship between Vitamin B12 and cobalt metabolism in domestic ruminant: an update. Animals, vol. 10, i. 10 (12 oct.), art. 1855. DOI: https://doi.org/10.3390/ani10101855.
Resumen : Cobalt, as a trace element, is essential for rumen microorganisms for the formation of vitamin B12. In the metabolism of mammals, vitamin B12 is an essential part of two enzymatic systems involved in multiple metabolic reactions, such as in the metabolism of carbohydrates, lipids, some amino acids and DNA. Adenosylcobalamin and methylcobalamin are coenzymes of methylmalonyl coenzyme A (CoA) mutase and methionine synthetase and are essential for obtaining energy through ruminal metabolism. Signs of cobalt deficiency range from hyporexia, reduced growth and weight loss to liver steatosis, anemia, impaired immune function, impaired reproductive function and even death. Cobalt status in ruminant animals can be assessed by direct measurement of blood or tissue concentrations of cobalt or vitamin B12, as well as the level of methylmalonic acid, homocysteine or transcobalamin in blood; methylmalonic acid in urine; some variables hematological; food consumption or growth of animals. In general, it is assumed that the requirement for cobalt (Co) is expressed around 0.11 ppm (mg/kg) in the dry matter (DM) diet; current recommendations seem to advise increasing Co supplementation and placing it around 0.20 mg Co/kg DM. Although there is no unanimous criterion about milk production, fattening or reproductive rates in response to increased supplementation with Co, in some investigations, when the total Co of the diet was approximately 1 to 1.3 ppm (mg/kg), maximum responses were observed in the milk production.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2076-2615/10/10/1855
Este artículo pertenece a la colección "Feeding cattle for health improvement".
URI : http://hdl.handle.net/10637/12487
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2076-2615 (Electrónico).
Aparece en las colecciones: Dpto. Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos

Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Relationship_Gonzalez_ANIMALS_2020.pdf3,96 MBAdobe PDFVisualizar/Abrir



Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.