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Título : Adipose-derived mesenchymal stem cells : a promising tool in the treatment of musculoskeletal diseases
Autor : Torres Torrillas, Marta.
Rubio Zaragoza, Mónica.
Damiá Giménez, Elena.
Cuervo Serrato, Belén.
Romero Martínez, Ayla de.
Peláez Gorrea, Pau.
Chicharro Alcántara, Deborah.
Miguel Pastor, Laura.
Sopena Juncosa, Joaquín Jesús.
Materias: Musculoskeletal system - Diseases - Treatment.Terapia celular.Stem cells - Therapeutic use.Células madre - Uso terapéutico.Sistema musculoesquelético - Enfermedades - Tratamiento.Cellular therapy.
Fecha de publicación : 25-jun-2019
Editorial : MDPI
Citación : Torres-Torrillas, M., Rubio, M., Damiá, E., Cuervo, B., Romero, A., Peláez, P. et al. (2019). Adipose-derived mesenchymal stem cells : a promising tool in the treatment of musculoskeletal diseases. International Journal of Molecular Sciences, vol. 20, n. 12, art. 3105 (25 jun.). DOI: https://doi.org/10.3390/ijms20123105
Resumen : Chronic musculoskeletal (MSK) pain is one of the most common medical complaintsworldwide and musculoskeletal injuries have an enormous social and economical impact. Currentpharmacological and surgical treatments aim to relief pain and restore function; however,unsatiscactory outcomes are commonly reported. In order to find an accurate treatment to suchpathologies, over the last years, there has been a significantly increasing interest in cellular therapies,such as adipose-derived mesenchymal stem cells (AMSCs). These cells represent a relatively newstrategy in regenerative medicine, with many potential applications, especially regarding MSKdisorders, and preclinical and clinical studies have demonstrated their efficacy in muscle, tendon,bone and cartilage regeneration. Nevertheless, several worries about their safety and side effects atlong-term remain unsolved. This article aims to review the current state of AMSCs therapy in thetreatment of several MSK diseases and their clinical applications in veterinary and human medicine.
Descripción : Este es el artículo que se ha publicado de forma definitiva en: https://www.mdpi.com/1422-0067/20/12/3105
URI : http://hdl.handle.net/10637/10851
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 1661-6596.
1422-0067 (Electrónico).
Aparece en las colecciones: Dpto. Medicina y Cirugía Animal

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