Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/10759
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.otherUCH. Departamento de Ciencias Biomédicas-
dc.contributor.otherProducción Científica UCH 2019-
dc.creatorHernández Rabaza, Vicente-
dc.creatorLópez Pedrajas, Rosa María-
dc.creatorAlmansa Frías, María Inmaculada-
dc.date2019-
dc.date.accessioned2019-12-14T05:01:20Z-
dc.date.available2019-12-14T05:01:20Z-
dc.date.issued2019-03-02-
dc.identifier.citationHernández-Rabaza, V., López-Pedrajas, R. & Almansa, I. (2019). Progesterone, Lipoic Acid, and Sulforaphane as promising antioxidants for retinal diseases : a review. Antioxidants, vol. 8, n. 3 (2 mar.), art. 53. DOI: https://doi.org/10.3390/antiox8030053-
dc.identifier.issn2076-3921 (Electrónico)-
dc.identifier.urihttp://hdl.handle.net/10637/10759-
dc.descriptionEste artículo se ha publicado de forma definitiva en: https://www.mdpi.com/2076-3921/8/3/53-
dc.descriptionEste artículo pertenece al número especial "Antioxidants and Retinal Disease".-
dc.description.abstractOxidative stress has been documented to be a key factor in the cause and progression of different retinal diseases. Oxidative cellular unbalance triggers a sequence of reactions which prompt cell degeneration and retinal dysfunction, both hallmarks of several retinal pathologies. There is no effective treatment, yet, for many retinal diseases. Antioxidant treatment have been pointed out to be an encouraging palliative treatment; the beneficial effects documented involve slowing the progression of the disease, a reduction of cell degeneration, and improvement of retinal functions. There is a vast information corpus on antioxidant candidates. In this review, we expose three of the main antioxidant treatments, selected for their promising results that has been reported to date. Recently, the sulforaphane, an isothiocyanate molecule, has been unveiled as a neuroprotective candidate, by its antioxidant properties. Progesterone, a neurosteroid has been proposed to be a solid and effective neuroprotective agent. Finally, the lipoic acid, an organosulfur compound, is a well-recognized antioxidant. All of them, have been tested and studied on different retinal disease models. In this review, we summarized the published results of these works, to offer a general view of the current antioxidant treatment advances, including the main effects and mechanisms described.-
dc.formatapplication/pdf-
dc.language.isoen-
dc.publisherMDPI-
dc.relationEste artículo ha recibido ayudas de la Universidad CEU Cardenal Herrera y de la Fundación Universitaria San Pablo CEU (INDI 18/31) y "Ayudas para la realización de proyectos de investigación+docencia en la Universidad CEU-Cardenal Herrera" (1808 IDOC).-
dc.relation.ispartofAntioxidants, vol. 8, n. 3 (2 mar. 2019).-
dc.rightshttp://creativecommons.org/licenses/by/4.0/deed.es-
dc.subjectRetina - Enfermedades - Factores de riesgo.-
dc.subjectRetina - Diseases - Risk factors.-
dc.subjectAntioxidantes.-
dc.subjectAntioxidants.-
dc.subjectProgesterona - Uso terapéutico.-
dc.subjectÁcido lipoico - Uso terapéutico.-
dc.subjectSulforafano - Uso terapéutico.-
dc.subjectRetina - Diseases - Treatment.-
dc.subjectSulforaphane - Therapeutic use.-
dc.subjectRetina - Enfermedades - Tratamiento.-
dc.subjectProgesterone - Therapeutic use.-
dc.subjectLipoic acid - Therapeutic use.-
dc.titleProgesterone, Lipoic Acid, and Sulforaphane as promising antioxidants for retinal diseases : a review-
dc.typeArtículo-
dc.identifier.doihttps://doi.org/10.3390/antiox8030053-
dc.relation.projectIDINDI 18/31-
dc.relation.projectID1808 IDOC-
dc.centroUniversidad Cardenal Herrera-CEU-
Aparece en las colecciones: Dpto. Ciencias Biomédicas




Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.