Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/10692
Título : Applying Loop-mediated Isothermal Amplification (LAMP) in the Diagnosis of Malaria, Leishmaniasis and Trypanosomiasis as Point-of-Care Tests (POCTs) / María Auxiliadora Dea Ayuela ... [et al.].
Autor : Dea Ayuela, María Auxiliadora.
Galiana Roselló, Cristina.
Lalatsa, Katerina.
Serrano López, Dolores Remedios.
Materias: Química farmacéutica.Pharmaceutical chemistry.Bioquímica clínica.Chagas, Enfermedad de - Diagnóstico.Clinical biochemistry.Malaria - Diagnosis.Leishmaniasis - Diagnosis.Paludismo - Diagnóstico.Trypanosomiasis - Diagnosis.Tripanosomiasis - Diagnóstico.Leishmaniasis - Diagnóstico.Chagas' disease - Diagnosis.
Fecha de publicación : 20-nov-2018
Editorial : Bentham Science.
Citación : Dea Ayuela, MA., Galiana-Roselló, C., Lalatsa, A. & Serrano, DR. (2018). Applying Loop-mediated Isothermal Amplification (LAMP) in the Diagnosis of Malaria, Leishmaniasis and Trypanosomiasis as Point-of-Care Tests (POCTs). Current Topics in Medicinal Chemistry, vol. 18, n. 16, pp. 1358-1374. DOI: https://doi.org/10.2174/1568026618666181025095735
Resumen : One of the main objectives of the WHO is controlling transmission of parasitic protozoa vector-borne diseases. A quick and precise diagnosis is critical in selecting the optimal therapeutic regime that avoids unnecessary treatments and the emergence of resistance. Molecular assays based on loopmediated isothermal amplification (LAMP) techniques are a good alternative to light microscopy and antigen-based rapid diagnostic tests in developing countries, since they allow for a large amount of genetic material generated from a few copies of DNA, and use primers that lead to high sensitivity and specificity, while the amplification process can be performed in isothermal conditions without the need of sophisticated equipment to interpret the results. In this review, the main advances in the development of LAMP assays for the diagnosis of malaria, leishmaniasis and Chagas' disease are discussed as well as the feasibility of their implementation in developing countries and use as point- of-care diagnostic tests.
Descripción : Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: http://www.eurekaselect.com/166607/article
This is the pre-peer reviewed version of the following article: Dea Ayuela, MA., Galiana-Roselló, C., Lalatsa, A. & Serrano, DR. (2018). Applying Loop-mediated Isothermal Amplification (LAMP) in the Diagnosis of Malaria, Leishmaniasis and Trypanosomiasis as Point-of-Care Tests (POCTs). Current Topics in Medicinal Chemistry, vol. 18, n. 16, pp. 1358-1374, which has been published in final form at https://doi.org/10.2174/1568026618666181025095735
Este es el post-print del siguiente artículo: Dea Ayuela, MA., Galiana-Roselló, C., Lalatsa, A. & Serrano, DR. (2018). Applying Loop-mediated Isothermal Amplification (LAMP) in the Diagnosis of Malaria, Leishmaniasis and Trypanosomiasis as Point-of-Care Tests (POCTs). Current Topics in Medicinal Chemistry, vol. 18, n. 16, pp. 1358-1374, que se ha publicado de forma definitiva en https://doi.org/10.2174/1568026618666181025095735
URI : http://hdl.handle.net/10637/10692
Derechos: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
ISSN : 1568-0266
1873-4294 (Electrónico)
Aparece en las colecciones: Dpto. Farmacia




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