Mutual influences between Nitric Oxide and Paraoxonase 1

dc.centroUniversidad Cardenal Herrera-CEU
dc.contributor.authorMoya, Carlos
dc.contributor.authorMáñez Aliño, Salvador
dc.contributor.authorMarín Vázquez, Marta
dc.contributor.otherUCH. Departamento de Farmacia
dc.contributor.otherProducción Científica UCH 2019
dc.date2019
dc.date.accessioned2020-03-12T05:00:10Z
dc.date.available2020-03-12T05:00:10Z
dc.date.issued2019-12-05
dc.descriptionEste artículo se ha publicado de forma definitiva en: https://www.mdpi.com/2076-3921/8/12/619
dc.descriptionEste artículo pertenece al número especial "Paraoxonase in Oxidation and Inflammation".
dc.description.abstractOne of the best consolidated paradigms in vascular pharmacology is that an uncontrolled excess of oxidizing chemical species causes tissue damage and loss of function in the endothelial and subendothelial layers. The fact that high-density lipoproteins play an important role in preventing such an imbalance is integrated into that concept, for which the expression and activity of paraoxonases is certainly crucial. The term paraoxonase (aryldialkyl phosphatase, EC 3.1.8.1) encompasses at least three distinct isoforms, with a wide variation in substrate a nity, cell and fluid localization, and biased expression of polymorphism. The purpose of this review is to determine the interactions that paraoxonase 1 has with nitric oxide synthase, its reaction product, nitric oxide (nitrogen monoxide, NO), and its derived reactive species generated in an oxidative medium, with a special focus on its pathological implications.
dc.formatapplication/pdf
dc.identifier.citationMarín Vázquez, M., Moya, C. and Máñez Aliño, S. (2019). Mutual influences between Nitric Oxide and Paraoxonase 1. Antioxidants, vol. 8, n. 12 (5 dec.), art. 619. DOI: https://doi.org/10.3390/antiox8120619
dc.identifier.doihttps://doi.org/10.3390/antiox8120619
dc.identifier.issn2076-3921 (Electrónico)
dc.identifier.urihttp://hdl.handle.net/10637/10790
dc.language.isoen
dc.publisherMDPI.
dc.relationEsta investigación ha recibido apoyo económico por parte de la Universitat de València.
dc.relation.ispartofAntioxidants, vol. 8, n. 12 (5 dec. 2019).
dc.rightsopen access
dc.rights.cchttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subjectAntioxidantes.
dc.subjectAntioxidants.
dc.subjectNitric oxide - Therapeutic use.
dc.subjectParaoxonasa - Uso terapéutico.
dc.subjectLipoproteínas.
dc.subjectVasculitis - Tratamiento.
dc.subjectVasculitis - Treatment.
dc.subjectÓxido nítrico - Uso terapéutico.
dc.subjectParaoxonase - Therapeutic use.
dc.subjectLipoproteins.
dc.titleMutual influences between Nitric Oxide and Paraoxonase 1
dc.typeArtículo
dspace.entity.typePublicationes
relation.isAuthorOfPublication9b4a0727-31c6-4cf9-baa5-203f13f5e6b9
relation.isAuthorOfPublication.latestForDiscovery9b4a0727-31c6-4cf9-baa5-203f13f5e6b9

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