Epigenetic alterations in canine malignant lymphoma: future and clinical outcomes

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dc.centroUniversidad Cardenal Herrera-CEU
dc.contributor.authorMarín García, Pablo Jesús
dc.contributor.authorLlobat Bordes, Maria Dolores
dc.contributor.authorMontaner Angoiti, Esperanza
dc.contributor.otherProducción Científica UCH 2023
dc.contributor.otherUCH. Departamento de Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos
dc.contributor.otherUCH. Departamento de Medicina y Cirugía Animal
dc.date.accessioned2024-07-15T06:54:47Z
dc.date.available2024-07-15T06:54:47Z
dc.date.issued2023-01-29
dc.descriptionEste artículo pertenece al número especial "Companion Animals’ Molecular Oncology".es_ES
dc.description.abstractCanine malignant lymphoma is a common neoplasia in dogs, and some studies have used dogs as a research model for molecular mechanisms of lymphomas in humans. In two species, chemotherapy is the treatment of choice, but the resistance to conventional anticancer drugs is frequent. The knowledge of molecular mechanisms of development and progression of neoplasia has expanded in recent years, and the underlying epigenetic mechanisms are increasingly well known. These studies open up new ways of discovering therapeutic biomarkers. Histone deacetylases and demethylase inhibitors could be a future treatment for canine lymphoma, and the use of microRNAs as diagnosis and prognosis biomarkers is getting closer. This review summarises the epigenetic mechanisms underlying canine lymphoma and their possible application as treatment and biomarkers, both prognostic and diagnostic.es_ES
dc.identifier.citationMontaner-Angoiti, E., Marín-García, P.J. & Llobat, L. (2023). Epigenetic alterations in canine malignant lymphoma: future and clinical outcomes. Animals, vol. 13, i. 3, art. 468 (29 jan.). DOI: https://doi.org/10.3390/ani13030468es_ES
dc.identifier.doihttps://doi.org/10.3390/ani13030468
dc.identifier.issn2076-2615 (Electrónico)
dc.identifier.urihttp://hdl.handle.net/10637/16063
dc.language.isoenes_ES
dc.publisherMDPIes_ES
dc.relation.ispartofAnimals, vol. 13, i. 3
dc.rightsopen access
dc.rights.cchttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subjectLinfomases_ES
dc.subjectlymphomases_ES
dc.subjectPerroses_ES
dc.subjectDogses_ES
dc.subjectTratamiento médicoes_ES
dc.subjectMedical treatmentes_ES
dc.subjectBiomarcadoreses_ES
dc.subjectBiomarkerses_ES
dc.subjectOncología veterinariaes_ES
dc.subjectVeterinary oncologyes_ES
dc.titleEpigenetic alterations in canine malignant lymphoma: future and clinical outcomeses_ES
dc.typeArtículoes_ES
dspace.entity.typePublicationes
relation.isAuthorOfPublicationc6fae3b2-b9e4-4ef3-b698-58001a20375d
relation.isAuthorOfPublication7622435f-15e8-4711-a586-934e932d8483
relation.isAuthorOfPublication.latestForDiscoveryc6fae3b2-b9e4-4ef3-b698-58001a20375d

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