Radwanski, MateuszSauro, SalvatoreLeski, MichalPuszkarz, Adam K.Sokolowski, JerzyHardan, LouisBourgi, RimLukomska-Szymanska, MonikaProducción Científica UCH 2022UCH. Departamento de Odontología2023-05-262023-05-262022-09-26Radwanski, M., Leski, M., Puszkarz, A. K., Sokolowski, J., Hardan, L., Bourgi, R., Sauro, S. & Lukomska-Szymanska, M. (2022). A Micro-CT analysis of initial and long-term pores volume and porosity of bioactive endodontic sealers. Biomedicines, vol. 10, i. 10 (26 sep.), art. 2403. DOI: https://doi.org/10.3390/biomedicines101024032227-9059 (Electrónico)http://hdl.handle.net/10637/14343Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2227-9059/10/10/2403Este artículo de investigación pertenece a la sección "Molecular and Translational Medicine".The evaluation of the porosities within the interface of root canals obturated with endodontics materials is extremely important for the long-term success of endodontic treatments. The aim of this study was to compare initial and long-term volume of pores (total, open, closed) and porosity (total, regional) of three bioactive endodontic sealers: GuttaFlow Bioseal, Total Fill BC Sealer, and Bio- Root RCS. Root canals were obturated with three “bioactive” sealers using the single-cone technique. The volume of open and closed pores and porosity were calculated using a micro-computed tomography (MCT) method. The measurements were performed after 7 days (initial) and after 6 months (long-term) of incubation. Statistical significance was considered at p < 0.05. The total volume of pores remained unchanged after the 6-month storage. GuttaFlow Bioseal exhibited significantly higher long-term volume in open pores than Total Fill BC Sealer. The total porosity in all the tested sealers presented no statistically significant change after the 6-month storage, except for BioRoot RCS. The total porosity values of this latter material significantly increased after long-term incubation, especially in the apical region. In conclusion, the use of bioactive sealers with excessive tendency to create porosities both in shorth- and long-term periods of storage may compromise the long-term success of endodontic treatments.application/pdfenopen accessGums and resins, synthetic in Dentistry.Dental materials.Terapéutica dental.Gomas y resinas sintéticas - Aplicaciones en Odontología.Endodoncia.Endodontics.Materiales dentales.Dental therapeutics.Artículohttps://doi.org/10.3390/biomedicines10102403https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es