Reetz, Manfred T.Agudo Torres, RubénUniversidad San Pablo-CEU. Departamento de Ciencias Farmacéuticas y de la SaludGrupo: Parasitología e Inmunología molecular con aplicación biotecnológica, diagnóstica y terapéutica (PARINM)2024-04-102024-04-102013-10-01Agudo R, Reetz MT. Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution. Chem Commun (Camb). 2013 Dec 4;49(93):10914-6. doi: 10.1039/c3cc46229c.1364-548Xhttp://hdl.handle.net/10637/15720Acceso a la información de la publicación, a través de la siguiente URL: DOI https://doi.org/10.1039/C3CC46229CDesigner cells for a synthetic cascade reaction harnessing selective redox reactions were devised, featuring two successive regioselective P450-catalyzed CH-activating oxidations of 1-cyclohexene carboxylic acid methyl ester followed by stereoselective olefin-reduction catalysed by (R)- or (S)-selective mutants of an enoate reductase.enmetadata only accessArtículo10.1039/C3CC46229Chttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es