López Rodríguez, María L.Porras, EstherBenhamú, BellindaRamos, José A.Morcillo, M. JoséLavandera Díaz, José Luis2013-11-012013-11-012000-11-01http://hdl.handle.net/10637/5540En: Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894x. v. 10, 2000, págs 1097-1100In order to make the rst contribution to the elucidation of essential structural features for 5-HT7 antagonism, a set of thirty 5-HT7 antagonists were selected from the literature. A pharmacophore model was built using Molecular Modeling studies with Catalyst program. The information contained in this model was validated with new synthesized compounds.application/pdfenCompuestos heterocíclicos.First pharmacophoric hypothesis for 5-HT7 antagonismArtículohttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es