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dc.contributor.otherUniversidad San Pablo-CEU. Facultad de Medicina.-
dc.contributor.otherGrupo: Enfermedades inmunológicas inflamatorias (ALLERGY)-
dc.creatorZubeldia Varela, Elisa-
dc.creatorIbáñez Sandín, María Dolores-
dc.creatorGómez Casado, Cristina-
dc.creatorPérez Gordo, Marina-
dc.date.accessioned2024-04-24T17:23:56Z-
dc.date.available2024-04-24T17:23:56Z-
dc.date.issued2024-02-23-
dc.identifier.citationZubeldia-Varela E, Ibáñez-Sandín MD, Gomez-Casado C and Pérez-Gordo M (2024) Allergy-associated biomarkers in early life identified by Omics techniques. Front. Allergy 5:1359142. doi: 10.3389/falgy.2024.1359142-
dc.identifier.issn2673-6101-
dc.identifier.urihttp://hdl.handle.net/10637/15752-
dc.description.abstractThe prevalence and severity of allergic diseases have increased over the last 30 years. Understanding the mechanisms responsible for these diseases is a major challenge in current allergology, as it is crucial for the transition towards precision medicine, which encompasses predictive, preventive, and personalized strategies. The urge to identify predictive biomarkers of allergy at early stages of life is crucial, especially in the context of major allergic diseases such as food allergy and atopic dermatitis. Identifying these biomarkers could enhance our understanding of the immature immune responses, improve allergy handling at early ages and pave the way for preventive and therapeutic approaches. This minireview aims to explore the relevance of three biomarker categories (proteome, microbiome, and metabolome) in early life. First, levels of some proteins emerge as potential indicators of mucosal health and metabolic status in certain allergic diseases. Second, bacterial taxonomy provides insight into the composition of the microbiota through high-throughput sequencing methods. Finally, metabolites, representing the end products of bacterial and host metabolic activity, serve as early indicators of changes in microbiota and host metabolism. This information could help to develop an extensive identification of biomarkers in AD and FA and their potential in translational personalized medicine in early life.es_ES
dc.formatapplication/pdf-
dc.language.isoen-
dc.publisherFrontiers Media-
dc.relation.ispartofFrontiers in Allergy-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es-
dc.rightsOpen Access-
dc.subjectAtopyen_EN
dc.subjectAtopic dermatitisen_EN
dc.subjectBiomarkersen_EN
dc.subjectEarly lifeen_EN
dc.subjectFood allergyen_EN
dc.subjectMetabolomeen_EN
dc.subjectMicrobiomeen_EN
dc.subjectProteomeen_EN
dc.titleAllergy-associated biomarkers in early life identified by Omics techniquesen_EN
dc.typeArtículo-
dc.identifier.doi10.3389/falgy.2024.1359142-
dc.centroUniversidad San Pablo-CEU-
Aparece en las colecciones: Medicina




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