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dc.contributor.otherUniversitat Abat Oliba CEU. Departament de Psicologia-
dc.creatorLaporta-Hoyos, Olga-
dc.creatorBallester-Plané, Júlia-
dc.creatorPóo, Pilar-
dc.creatorMacaya, Alfons-
dc.creatorMeléndez-Plumed, Mar-
dc.creatorVázquez, Élida-
dc.creatorDelgado, Ignacio-
dc.creatorZubiaurre-Elorza, Leire-
dc.creatorBotellero, Violeta L.-
dc.creatorNarberhaus, Ana-
dc.creatorToro-Tamargo, Esther-
dc.creatorSegarra, Dolors-
dc.creatorPueyo, Roser-
dc.date2017-
dc.date.accessioned2024-01-25T16:03:34Z-
dc.date.available2024-01-25T16:03:34Z-
dc.date.issued2016-10-20-
dc.identifier.citationLaporta-Hoyos, O.; Ballester-Plane, J.; Poo, P.; Macaya, A.; Melendez-Plumed, M.; Vazquez, E.; Delgado, I.; Zubiaurre-Elorza, L.; Botellero, V. L.; Narberhaus, A.; Toro-Tamargo, E.; Segarra, D.; Pueyo, R. (2017) Proxy-reported quality of life in adolescents and adults with dyskinetic cerebral palsy is associated with executive functions and cortical thickness. QUALITY OF LIFE RESEARCH. 26 - 5, pp. 1209 - 1222. https://doi.org/10.1007/s11136-016-1433-0es_ES
dc.identifier.issn1573-2649-
dc.identifier.urihttp://hdl.handle.net/10637/15125-
dc.descriptionEste artículo no está en acceso abierto por la política del editorial-
dc.description.abstractPurpose Quality of life (QOL) is a key outcome for people with cerebral palsy (CP), and executive functioning is an important predictor of QOL in other health-related conditions. Little is known about this association in CP or about its neural substrate. We aim to analyze the influence of executive functioning (including cognitive flexibility) as well as that of other psychological, motor, communication and socioeconomic variables on QOL and to identify neuroanatomical areas related to QOL in adolescents and adults with CP. Methods Fifty subjects diagnosed with dyskinetic CP (mean age 25.96 years) were recruited. Their caregivers completed the primary caregiver proxy report version of the CP QOL-Teen questionnaire. Motor status, communication, IQ, four executive function domains, anxiety/depression and socioeconomic status were evaluated. Correlations and multiple linear regression models were used to relate CP QOL domains and total score to these variables. Thirty-six participants underwent an MRI assessment. Correlations were examined between cortical thickness and CP QOL total score and between cortical thickness and variables that might predict the CP QOL total score. Results Executive functions predict scores in four domains of CP QOL (General well-being and participation, Communication and physical health, Family health and Feelings about functioning) in the regression model. Among the cognitive domains that comprise executive function, only cognitive flexibility measured in terms of performance on the Wisconsin card sorting test (WCST) predicts the CP QOL total score. Monthly income, fine motor functioning and communication ability predict scores on the domains Access to services and Family Health, Feelings about functioning and School well-being, respectively. The clusters resulting from the correlation between cortical thickness and both CP QOL total score and WCST performance overlapped in the posterior cingulate and precuneus cortices. Conclusions Cognitive flexibility predicts proxy report CP QOL-Teen total score in dyskinetic CP. This relationship has its anatomical correlate in the posterior cingulate and precuneus cortices.es_ES
dc.formatapplication/pdf-
dc.language.isoenes_ES
dc.publisherSpringeres_ES
dc.relation.ispartofQuality of Life Research-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es-
dc.subjectCerebral palsyen_EN
dc.subjectCortical thicknessen_EN
dc.subjectExecutive functionsen_EN
dc.subjectMagnetic resonance imagingen_EN
dc.subjectQuality of lifeen_EN
dc.titleProxy-reported quality of life in adolescents and adults with dyskinetic cerebral palsy is associated with executive functions and cortical thicknessen_EN
dc.typeArtículoes_ES
dc.identifier.doi10.1007/s11136-016-1433-0-
dc.relation.projectIDThis study was funded by Ministerio de Ciencia e Innovacio ´n (Grant No. PSI2011/24386). First author has received a research grant from Ministerio de educacio´n, cultura y deporte of the government of Spain (Grant No. FPU13/06435). Second author has received a research grant from Age`ncia de Gestio´ d’Ajuts Universitaris i de Recerca of the government of Catalonia (Grant code FIDGR 2014).en_EN
dc.centroUniversitat Abat Oliba CEU-
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