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dc.contributor.otherProducción Científica UCH 2022-
dc.contributor.otherUCH. Departamento de Ciencias Biomédicas-
dc.contributor.otherUCH. Departamento de Farmacia-
dc.contributor.otherUCH. Departamento de Medicina y Cirugía-
dc.creatorPadilla Blanco, Miguel-
dc.creatorGucciardi, Francesca-
dc.creatorGuercio, Annalisa-
dc.creatorRubio Zamora, Vicente-
dc.creatorPrinciotta, Antonina-
dc.creatorVeses Jiménez, Verónica.-
dc.creatorSheth Shah, Chirag Chandrakant-
dc.creatorPascual Ortiz, Marina-
dc.creatorMaiques Fernández, Elisa-
dc.creatorRubio Guerri, Consuelo-
dc.date2022-
dc.date.accessioned2023-05-13T04:00:48Z-
dc.date.available2023-05-13T04:00:48Z-
dc.date.issued2022-04-26-
dc.identifier.citationPadilla-Blanco, M., Gucciardi, F., Guercio, A., Rubio, V., Princiotta, A., Veses, V., Terrana, M., Sheth, C. C., Pascual-Ortiz, M., Maiques, E., Purpari, G. & Rubio-Guerri, C. (2022). Pilot investigation of SARS-CoV-2 variants in the island of Sicily prior to and in the second wave of the COVID-19 pandemic. Frontiers in Microbiology, vol. 13, art. 869559 (26 apr.). DOI: https://doi.org/10.3389/fmicb.2022.869559-
dc.identifier.issn1664-302X (Electrónico)-
dc.identifier.urihttp://hdl.handle.net/10637/14268-
dc.descriptionEste artículo se encuentra disponible en la siguiente URL: https://www.frontiersin.org/articles/10.3389/fmicb.2022.869559/full-
dc.descriptionEn este artículo de investigación también participan: Francesca Gucciardi, Annalisa Guercio, Vicente Rubio, Antonina Princiotta, Verónica Veses, Mariangela Terrana, Chirag C. Sheth, Marina Pascual-Ortiz, Elisa Maiques, Giuseppa Purpari y Consuelo Rubio-Guerri.-
dc.descriptionEste artículo de investigación se encuentra en la sección "Virology".-
dc.description.abstractAfter 2 years of the COVID-19 pandemic, we continue to face vital challenges stemming from SARS-CoV-2 variation, causing changes in disease transmission and severity, viral adaptation to animal hosts, and antibody/vaccine evasion. Since the monitoring, characterization, and cataloging of viral variants are important and the existing information on this was scant for Sicily, this pilot study explored viral variants circulation on this island before and in the growth phase of the second wave of COVID-19 (September and October 2020), and in the downslope of that wave (early December 2020) through sequence analysis of 54 SARS-CoV-2-positive samples. The samples were nasopharyngeal swabs collected from Sicilian residents by a state-run one-health surveillance laboratory in Palermo. Variant characterization was based on RT-PCR amplification and sequencing of four regions of the viral genome. The B.1.177 variant was the most prevalent one, strongly predominating before the second wave and also as the wave downsized, although its relative prevalence decreased as other viral variants, particularly B.1.160, contributed to virus circulation. The occurrence of the B.1.160 variant may have been driven by the spread of that variant in continental Europe and by the relaxation of travel restrictions in the summer of 2020. No novel variants were identified. As sequencing of the entire viral genome in Sicily for the period covered here was restricted to seven deposited viral genome sequences, our results shed some light on SARS-CoV-2 variant circulation during that wave in this insular region of Italy which combines its partial insular isolation with being a major entry point for the African immigration.-
dc.formatapplication/pdf-
dc.languagees-
dc.language.isoen-
dc.publisherFrontiers Media-
dc.relationEste artículo de investigación ha sido financiado por la “Agencia Valenciana de Innovación: COVID-19. Ayudas de concesión directa a soluciones científico-innovadoras directamente relacionadas con la lucha contra la COVID-19” (COVID-19-203). Además, fue financiado por la Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital a través de Subvenciones a grupos de investigación emergentes (GV/2021/163), una ayuda de la Agencia Estatal de Investigación (AEI) del Gobierno de España (PID2020-120322RB-C21) y de los fondos Next Generation EU a través de la plataforma Salud Global del CSIC del Ministerio de Ciencia e Innovación del Gobierno de España (MCIN/AEI/10.13039/501100011033), así como una ayuda del Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri” por el proyecto “COVID-19: Traiettorie E.-
dc.relationUCH. Financiación Autonómica-
dc.relation.ispartofFrontiers in Microbiology, vol. 13 (26 apr. 2022)-
dc.rightshttp://creativecommons.org/licenses/by/4.0/deed.es-
dc.subjectCOVID-19 Pandemic, 2020--
dc.subjectCOVID-19.-
dc.subjectPandemia de la Covid-19, 2020--
dc.subjectSARS-CoV-2 (Virus)-
dc.subjectCOVID-19 (Disease)-
dc.titlePilot investigation of SARS-CoV-2 variants in the island of Sicily prior to and in the second wave of the COVID-19 pandemic-
dc.typeArtículo-
dc.identifier.doihttps://doi.org/10.3389/fmicb.2022.869559-
dc.relation.projectIDCOVID-19-203-
dc.relation.projectIDGV/2021/163-
dc.relation.projectIDPID2020-120322RB-C21-
dc.centroUniversidad Cardenal Herrera-CEU-
Aparece en las colecciones: Dpto. Ciencias Biomédicas




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