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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.other | Producción Científica UCH 2021 | - |
dc.contributor.other | UCH. Departamento de Ciencias Biomédicas | - |
dc.creator | Reula Martín, Ana | - |
dc.creator | Pitarch Fabregat, Javier | - |
dc.creator | Milara, Javier | - |
dc.creator | Cortijo Gimeno, Julio | - |
dc.creator | Mata Roig, Manuel | - |
dc.creator | Milian Medina, Lara | - |
dc.creator | Armengot, Miguel | - |
dc.date | 2021 | - |
dc.date.accessioned | 2022-04-05T04:00:24Z | - |
dc.date.available | 2022-04-05T04:00:24Z | - |
dc.date.issued | 2021-07-20 | - |
dc.identifier.citation | Reula, A., Pitarch-Fabregat, J., Milara, J., Cortijo, J., Mata-Roig, M., Milian, L. & Armengot, M. (2021). High-speed video microscopy for Primary Ciliary Dyskinesia diagnosis: a study of ciliary motility variations with time and temperature. Diagnostics, vol. 11, i. 7 (20 jul.), art. 1301. DOI: https://doi.org/10.3390/diagnostics11071301 | - |
dc.identifier.issn | 2075-4418 (Electrónico) | - |
dc.identifier.uri | http://hdl.handle.net/10637/13609 | - |
dc.description | Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2075-4418/11/7/1301 | - |
dc.description | Este artículo de investigación pertenece al número especial "Progress in Diagnosing and Managing Primary Ciliary Dyskinesia". | - |
dc.description.abstract | Primary ciliary dyskinesia (PCD) is a rare disease resulting from a defect in ciliary function that generates, among other issues, chronic upper and lower respiratory tract infections. European guidelines recommend studying ciliary function (pattern (CBP) and frequency (CBF)), together with characteristic clinical symptoms, as one of the definitive tests. However, there is no “gold standard”. The present study aims to use high-speed video microscopy to describe how CBF and CBP alter over time and at different temperatures to reduce the error rate in the diagnosis of PCD. Samples of nasal epithelium from 27 healthy volunteers were studied to assess CBF and CBP at 0, 3, 24, 48, and 72 h, at room temperature and 4 C. It was observed that CBF increased while CBP became dyskinetic, both at room temperature and at 4 C, as time passed, especially after 3 h. In order to preserve all ciliary function parameters and to perform a reliable analysis to improve the diagnostic process of PCD, analysis should be performed within the first 3 h of sample collection, preferably in reference centers. | - |
dc.format | application/pdf | - |
dc.language.iso | en | - |
dc.language.iso | es | - |
dc.publisher | MDPI | - |
dc.relation | Este trabajo de investigación fue financiado por el Fondo Europeo de Desarrollo Regional (FEDER), por el Instituto de Salud Carlos III (FIS PI16/01315, FIS PI17/02158, FIS PI19/00949, JR18/00050, SAF2017-82913-R), por el CIBERES (CB06/06/0027) del Gobierno de España y por una beca PROMETEO 2017/023/UV de la Generalitat Valenciana. | - |
dc.relation.ispartof | Diagnostics, vol. 11, n. 7 (20 jul. 2021) | - |
dc.rights | http://creativecommons.org/licenses/by/4.0/deed.es | - |
dc.subject | Microscopy. | - |
dc.subject | Microscopia. | - |
dc.subject | Kartagener, Síndrome de - Diagnóstico. | - |
dc.subject | Kartagener's syndrome - Diagnosis. | - |
dc.subject | Primary ciliary dyskinesia - Diagnosis. | - |
dc.subject | Aparato respiratorio - Enfermedades en los niños. | - |
dc.subject | Pediatric otolaryngology. | - |
dc.subject | Otorrinolaringología pediátrica. | - |
dc.subject | Enfermedades crónicas en los niños. | - |
dc.subject | Respiratory organs - Diseases in children. | - |
dc.subject | Chronic diseases in children. | - |
dc.subject | Disquinesia ciliar, Síndrome de - Diagnóstico. | - |
dc.title | High-speed video microscopy for Primary Ciliary Dyskinesia diagnosis : a study of ciliary motility variations with time and temperature | - |
dc.type | Artículo | - |
dc.identifier.doi | https://doi.org/10.3390/diagnostics11071301 | - |
dc.relation.projectID | FIS PI16/01315 | - |
dc.relation.projectID | FIS PI17/02158 | - |
dc.relation.projectID | FIS PI19/00949 | - |
dc.relation.projectID | JR18/00050 | - |
dc.relation.projectID | SAF2017-82913-R | - |
dc.relation.projectID | CB06/06/0027 | - |
dc.relation.projectID | 2017/023/UV | - |
dc.centro | Universidad Cardenal Herrera-CEU | - |
Aparece en las colecciones: | Dpto. Ciencias Biomédicas |
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