Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10637/12582Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.other | Producción Científica UCH 2020 | - |
| dc.contributor.other | UCH. Departamento de Farmacia | - |
| dc.creator | Alcaraz Tormo, María José | - |
| dc.creator | Compañ, Álvaro | - |
| dc.creator | Guillén Salazar, María Isabel | - |
| dc.date | 2020 | - |
| dc.date.accessioned | 2021-05-12T04:00:09Z | - |
| dc.date.available | 2021-05-12T04:00:09Z | - |
| dc.date.issued | 2019-12-31 | - |
| dc.identifier.citation | Alcaraz, M.J., Compañ, A. & Guillén, M.I. (2019). Extracellular vesicles from mesenchymal stem cells as novel treatments for musculoskeletal diseases. Cells, vol. 9, i. 1 (31 dec.), art. 98. DOI: https://doi.org/10.3390/cells9010098 | - |
| dc.identifier.issn | 2073-4409 (Electrónico) | - |
| dc.identifier.uri | http://hdl.handle.net/10637/12582 | - |
| dc.description | Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2073-4409/9/1/98 | - |
| dc.description | Este artículo pertenece al número especial "Therapeutic applications of extracellular vesicles". | - |
| dc.description.abstract | Mesenchymal stem/stromal cells (MSCs) represent a promising therapy for musculoskeletal diseases. There is compelling evidence indicating that MSC e ects are mainly mediated by paracrine mechanisms and in particular by the secretion of extracellular vesicles (EVs). Many studies have thus suggested that EVs may be an alternative to cell therapy with MSCs in tissue repair. In this review, we summarize the current understanding of MSC EVs actions in preclinical studies of (1) immune regulation and rheumatoid arthritis, (2) bone repair and bone diseases, (3) cartilage repair and osteoarthritis, (4) intervertebral disk degeneration and (5) skeletal muscle and tendon repair. We also discuss the mechanisms underlying these actions and the perspectives of MSC EVs-based strategies for future treatments of musculoskeletal disorders. | - |
| dc.format | application/pdf | - |
| dc.language.iso | es | - |
| dc.language.iso | en | - |
| dc.publisher | MDPI | - |
| dc.relation | Este trabajo de investigación ha sido financiado a través de una beca del Ministerio de Ciencia, Innovación y Universidades del Gobierno de España y de Fondos FEDER (SAF2017-85806-R). | - |
| dc.relation | UCH. Financiación Europea | - |
| dc.relation | UCH. Financiación Nacional | - |
| dc.relation.ispartof | Cells, vol. 9, n. 1. | - |
| dc.rights | http://creativecommons.org/licenses/by/4.0/deed.es | - |
| dc.subject | Osteoartritis - Tratamiento. | - |
| dc.subject | Osteoarthritis - Treatment. | - |
| dc.subject | Stem cells - Therapeutic use. | - |
| dc.subject | Sistema musculoesquelético - Enfermedades - Tratamiento. | - |
| dc.subject | Musculoskeletal system - Diseases - Treatment. | - |
| dc.subject | Células madre - Uso terapéutico. | - |
| dc.title | Extracellular vesicles from mesenchymal stem cells as novel treatments for musculoskeletal diseases | - |
| dc.type | Artículo | - |
| dc.identifier.doi | https://doi.org/10.3390/cells9010098 | - |
| dc.relation.projectID | SAF2017-85806-R | - |
| dc.centro | Universidad Cardenal Herrera-CEU | - |
| Aparece en las colecciones: | Dpto. Farmacia | |
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.