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dc.contributor.otherUCH. Departamento de Medicina y Cirugía Animal-
dc.creatorLópez Nájera, Diego-
dc.creatorRubio Zaragoza, Mónica.-
dc.creatorSopena Juncosa, Joaquín Jesús.-
dc.creatorAlentorn Geli, Eduard-
dc.creatorCugat Bertomeu, Ramón-
dc.creatorFernández Sarmiento, José Andrés-
dc.creatorDomínguez Pérez, Juan Manuel-
dc.creatorGarcía Balletbó, Montserrat-
dc.creatorPrimo Capella, Víctor J.-
dc.creatorCarrillo Poveda, José María.-
dc.date2016-
dc.date.accessioned2019-09-26T04:00:12Z-
dc.date.available2019-09-26T04:00:12Z-
dc.date.issued2016-12-01-
dc.identifier.citationLópez-Nájera, D., Rubio-Zaragoza, M., Sopena-Juncosa, JJ., Aletorn-Geli, E., Cugat-Bertomeu, R., Fernández-Sarmiento, JA. et al. (2016). Effects of plasma rich in growth factors (PRGF) on biomechanical properties of Achilles tendon repair. Knee Surgery, Sports Traumatology, Arthroscopy, vol. 24 (dec. 2016), n. 12, pp. 3997-4004. DOI: https://doi.org/10.1007/s00167-015-3725-2-
dc.identifier.issn0942-2056-
dc.identifier.issn1433-7347 (Electrónico)-
dc.identifier.urihttp://hdl.handle.net/10637/10612-
dc.descriptionEsta es la versión pre-print del artículo que se encuentra disponible en la página web de la revista en la siguiente URL: https://link.springer.com/article/10.1007/s00167-015-3725-2-
dc.description.abstractTo assess the biomechanical effects of intra-tendinous injections of PRGF on the healing Achilles tendon after repair in a sheep model. Thirty sheep were randomly assigned into one of the six groups depending on the type of treatment 10 received (PRGF or placebo) and survival time (2, 4 and 8 weeks). The Achilles tendon injury was repaired by suturing the tendinous edges employing a three-loop pulley pattern. A trans-articular external fixation system was then used for immobilization. The PRGF or placebo was administered on a weekly basis completing a maximum of 3 infiltrations. The force, section and tension values were compared between the operated and healthy Achilles tendons across all groups. The PRGF-treated tendons had higher force at eight weeks compared with the placebo group (p=0.007). Between two and four weeks, a significant increase in force in both the PRGF-treated tendon (p=0.0027) and placebo group (p=0.0095) occurred. No significant differences were found for section ratio between PRGF-treated tendons and the placebo group for any of the time periods evaluated. At 2 weeks PRGF-treated tendons had higher tension ratio compared to placebo group tendons (p=0.0143). Both PRGF and placebo treatments significantly improved the force (p<0.001 and p=0.0095, respectively) and tension (p=0.009 and p=0.0039, respectively) ratios at 8 compared to 2 weeks. The application of PRGF increases Achilles tendon repair strength at 8 weeks compared to the use of placebo. The use of PRGF does not modify section and tension ratios compared to placebo at 8 weeks. The tension ratio progressively increases between two and eight weeks compared with the placebo. PRGF can be used in the clinical setting as a complementary therapy to improve the repair strength of acute Achilles tendon ruptures.-
dc.formatapplication/pdf-
dc.language.isoen-
dc.publisherSpringer Nature.-
dc.relation.ispartofKnee Surgery, Sports Traumatology, Arthroscopy, vol. 24 (dec. 2016), n. 12.-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es-
dc.subjectTendón de Aquiles - Regeneración.-
dc.subjectBlood plasma - Therapeutic use.-
dc.subjectCrecimiento - Factores - Uso terapéutico.-
dc.subjectPlasma sanguíneo - Uso terapéutico.-
dc.subjectAchilles tendon - Biomechanics.-
dc.subjectTendón de Aquiles - Heridas y lesiones - Tratamiento.-
dc.subjectAchilles tendon - Regeneration.-
dc.subjectAchilles tendon - Wounds and injuries - Treatment.-
dc.subjectTendón de Aquiles - Propiedades mecánicas.-
dc.subjectGrowth factors - Therapeutic use.-
dc.titleEffects of plasma rich in growth factors (PRGF) on biomechanical properties of Achilles tendon repair-
dc.typeArtículo-
dc.description.versionEste es el pre-print del siguiente artículo: López-Nájera, D., Rubio-Zaragoza, M., Sopena-Juncosa, JJ., Aletorn-Geli, E., Cugat-Bertomeu, R., Fernández-Sarmiento, JA. et al. (2016). Effects of plasma rich in growth factors (PRGF) on biomechanical properties of Achilles tendon repair. Knee Surgery, Sports Traumatology, Arthroscopy, vol. 24 (dec. 2016), n. 12, pp. 3997-4004, que se ha publicado de forma definitiva en https://doi.org/10.1007/s00167-015-3725-2-
dc.description.versionThis is the pre-peer reviewed version of the following article: López-Nájera, D., Rubio-Zaragoza, M., Sopena-Juncosa, JJ., Aletorn-Geli, E., Cugat-Bertomeu, R., Fernández-Sarmiento, JA. et al. (2016). Effects of plasma rich in growth factors (PRGF) on biomechanical properties of Achilles tendon repair. Knee Surgery, Sports Traumatology, Arthroscopy, vol. 24 (dec. 2016), n. 12, pp. 3997-4004, which has been published in final form at https://doi.org/10.1007/s00167-015-3725-2-
dc.identifier.doihttps://doi.org/10.1007/s00167-015-3725-2-
dc.centroUniversidad Cardenal Herrera-CEU-
Aparece en las colecciones: Dpto. Medicina y Cirugía Animal




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