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Fluorouracil_Agudo_Arias_Domingo_2009.PNG.jpg29-jun-20095-fluorouracil in lethal mutagenesis of foot-and-mouth disease virusAgudo Torres, Rubén; Arias, Armando; Domingo, EstebanArtículo
Multi-Step_Agudo_et_al_PlosPatho_2010.pdf.jpg26-ago-2010A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-EscapeAgudo Torres, Rubén; Ferrer-Orta, Cristina; Arias, Armando; Higuera, Ignacio de la; Perales, Celia; Pérez-Luque, Rosa; Verdaguer, Nuria; Esteban, DomingoArtículo
Achieving_Agudo_Dor_Reetz_ChemBio_2012.pdf.jpg9-jul-2012Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed EvolutionAgudo Torres, Rubén; Roiban, Gheorghe-Doru; Reetz, Manfred T.Artículo
CH-activating_Doru_et_al_Chem_Comm_2014.pdf.jpg22-ago-2014CH-activating oxidative hydroxylation of 1-tetralones and related compounds with high regio- and stereoselectivityAgudo Torres, Rubén; Roiban, Gheorghe-Doru; Ilie, Adriana; Lonsdale, Richard; Reetz, Manfred T.Artículo
Counteracting_Perales_agudo_Domingo_PlosOne_2009.pdf.jpg14-may-2009Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic TreatmentPerales, Celia; Agudo Torres, Rubén; Domingo, EstebanArtículo
Cytochrome_Doru_Agudo_Reetz_Angewandte_2014.pdf.jpg2014Cytochrome P450 catalyzed oxidative hydroxylation of achiral organic compounds with simultaneous creation of two chirality centers in a single C-H activation stepRoiban, Gheorghe-Doru; Agudo Torres, Rubén; Reetz, Manfred T.Artículo
Desarrollo_Yanira_Sáez_USPCEU_Tesis_2022.pdf.jpg30-abr-2022Desarrollo y aplicación de métodos basados en fluorescencia para la determinación rápida de la actividad de las polimerasas de virus ARNSáez Álvarez, YaniraTesis
Designer_Agudo_Reetz_Camb_2013.PNG.jpg1-oct-2013Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolutionAgudo Torres, Rubén; Reetz, Manfred T.Artículo
Development_Saez_et_al_Sci_Repo_2019.pdf.jpg1-abr-2019Development of a fluorescence-based method for the rapid determination of Zika virus polymerase activity and the screening of antiviral drugsSáez Álvarez, Yanira; Arias, Armando; Del Águila, Carmen; Agudo Torres, RubénArtículo
Directed_Parra_Agudo_Reetz_ChemBio_2013.pdf.jpg25-nov-2013Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue SitesAgudo Torres, Rubén; Parra, Loreto P.; Reetz, Manfred T.Artículo
Directed_Acevedo_Agudo_Reetz_JorBio_2014.PNG.jpg29-abr-2014Directed evolution of stereoselective enzymes based on geneticselection as opposed to screening systemsAcevedo-Rocha, Carlos G; Agudo Torres, Rubén; Reetz, Manfred T.Artículo
Engineering_Agudo_et_al_Nucl_Acids_Rese_2017.pdf.jpg26-jul-2017Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymeraseAgudo Torres, Rubén; Calvo, Patricia A.; María I. Martínez Jiménez; Blanco, LuisArtículo
Foot_Sierra_et_al_Jor_Viro_2007.pdf.jpg6-dic-2006Foot-and-Mouth Disease Virus Mutant with Decreased Sensitivity to Ribavirin: Implications for Error CatastropheSierra, Macarena; Airaksinen, Antero; González-López, Claudia; Agudo Torres, Rubén; Arias, Armando; Domingo, EstebanArtículo
Identification_Garcia_et_al_Anti_Rese_2023.pdf.jpg24-feb-2023Identification of West Nile virus RNA-dependent RNA polymerase non-nucleoside inhibitors by real-time high throughput fluorescence screeningGarcía Zarandieta, Marta; Quesada, Ernesto; Martínez Jiménez, María I.; Newnes, Crsitina V.; Fernández Caballero, Víctor; Sáez Álvarez, Yanira; Blázquez, Ana Belén; Escribano Romero, Estela; Sáiz, Juan Carlos; Del Águila, Carmen; Martín Acebes, Miguel A.; Pérez Pérez, María Jesús; Agudo Torres, RubénArtículo
Induced_Agudo_et_al_JACS_2013.PNG.jpg6-feb-2013Induced axial chirality in biocatalytic asymmetric ketone reductionAgudo Torres, Rubén; Roiban, Gheorghe-Doru; Reetz, Manfred T.Artículo
Influence_Perales_et_al_JMolBiol_2011.PNG.jpg19-ene-2011Influence of Mutagenesis and Viral Load on the Sustained Low-Level Replication of an RNA VirusPerales, Celia; Agudo Torres, Rubén; Manrubia, Susanna C.; Domingo, EstebanArtículo
Involvement_Agudo_et_al_Virology_2016.pdf.jpg29-abr-2016Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanismAgudo Torres, Rubén; Higuera, Ignacio de la; Arias, Armando; Grande Pérez, Ana; Domingo, EstebanArtículo
Molecular_Arias_et_al_Jou_GenViro_2013.pdf.jpg1-abr-2013Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational loadAgudo Torres, Rubén; Arias, Armando; Isabel de Ávila, Ana; Sanz Ramos, Marta; Escarmís, Cristina; Domingo, EstebanArtículo
Novel_Saez_et_al_Anti_AgentsChe_2021.pdf.jpg17-ago-2021Novel nonnucleoside inhibitors of Zika Virus polymerase Identified through the screening of an open library of antikinetoplastid compoundsSáez Álvarez, Yanira; Jiménez de Oya, Nereida; Del Águila, Carmen; Sáiz, Juan Carlos; Arias, Armando; Agudo Torres, Rubén; Martín Acebes, Miguel A.Artículo
Potential_Perales_et_al_PlosPatho_2009.pdf.jpg13-nov-2009Potential Benefits of Sequential Inhibitor-Mutagen Treatments of RNA Virus InfectionsPerales, Celia; Agudo Torres, Rubén; Tejero Franco, Héctor; Manrubia, Susanna C.; Domingo, EstebanArtículo