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Engineering_Agudo_et_al_Nucl_Acids_Rese_2017.pdf.jpg26-jul-2017Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymeraseAgudo Torres, Rubén; Calvo, Patricia A.; María I. Martínez Jiménez; Blanco, LuisArtículo
Foot_Sierra_et_al_Jor_Viro_2007.pdf.jpg6-dic-2006Foot-and-Mouth Disease Virus Mutant with Decreased Sensitivity to Ribavirin: Implications for Error CatastropheSierra, Macarena; Airaksinen, Antero; González-López, Claudia; Agudo Torres, Rubén; Arias, Armando; Domingo, EstebanArtículo
Identification_Garcia_et_al_Anti_Rese_2023.pdf.jpg24-feb-2023Identification of West Nile virus RNA-dependent RNA polymerase non-nucleoside inhibitors by real-time high throughput fluorescence screeningGarcía Zarandieta, Marta; Quesada, Ernesto; Martínez Jiménez, María I.; Newnes, Crsitina V.; Fernández Caballero, Víctor; Sáez Álvarez, Yanira; Blázquez, Ana Belén; Escribano Romero, Estela; Sáiz, Juan Carlos; Del Águila, Carmen; Martín Acebes, Miguel A.; Pérez Pérez, María Jesús; Agudo Torres, RubénArtículo
Induced_Agudo_et_al_JACS_2013.PNG.jpg6-feb-2013Induced axial chirality in biocatalytic asymmetric ketone reductionAgudo Torres, Rubén; Roiban, Gheorghe-Doru; Reetz, Manfred T.Artículo
Influence_Perales_et_al_JMolBiol_2011.PNG.jpg19-ene-2011Influence of Mutagenesis and Viral Load on the Sustained Low-Level Replication of an RNA VirusPerales, Celia; Agudo Torres, Rubén; Manrubia, Susanna C.; Domingo, EstebanArtículo
Involvement_Agudo_et_al_Virology_2016.pdf.jpg29-abr-2016Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanismAgudo Torres, Rubén; Higuera, Ignacio de la; Arias, Armando; Grande Pérez, Ana; Domingo, EstebanArtículo
Molecular_Arias_et_al_Jou_GenViro_2013.pdf.jpg1-abr-2013Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational loadAgudo Torres, Rubén; Arias, Armando; Isabel de Ávila, Ana; Sanz Ramos, Marta; Escarmís, Cristina; Domingo, EstebanArtículo
Novel_Saez_et_al_Anti_AgentsChe_2021.pdf.jpg17-ago-2021Novel nonnucleoside inhibitors of Zika Virus polymerase Identified through the screening of an open library of antikinetoplastid compoundsSáez Álvarez, Yanira; Jiménez de Oya, Nereida; Del Águila, Carmen; Sáiz, Juan Carlos; Arias, Armando; Agudo Torres, Rubén; Martín Acebes, Miguel A.Artículo
Catalyzed_Ilie_et_al_Tetrah_2015.PNG.jpg2-dic-2014P450-catalyzed regio- and stereoselective oxidative hydroxylation of disubstituted cyclohexanes: creation of three centers of chirality in a single CH-activation eventIlie, Adriana; Agudo Torres, Rubén; Roiban, Gheorghe-Doru; Reetz, Manfred T.Artículo
Potential_Perales_et_al_PlosPatho_2009.pdf.jpg13-nov-2009Potential Benefits of Sequential Inhibitor-Mutagen Treatments of RNA Virus InfectionsPerales, Celia; Agudo Torres, Rubén; Tejero Franco, Héctor; Manrubia, Susanna C.; Domingo, EstebanArtículo
Stereo_Rooban_Agudo_Reetz_Tetra_2013.PNG.jpg6-may-2013Stereo- and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexeneRoiban, Gheorghe-Doru; Agudo Torres, Rubén; Reetz, Manfred T.Artículo
Structural_Ferrer_et_al_CurrOpi_StructBio_2009.PNG.jpg13-nov-2009Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymeraseFerrer-Orta, Cristina; Agudo Torres, Rubén; Domingo, Esteban; Verdaguer, NuriaArtículo
Structure_Ferrer_et_al_EMBO_2006.pdf.jpg2-feb-2006The structure of a protein primer–polymerase complex in the initiation of genome replicationFerrer-Orta, Cristina; Arias, Armando; Agudo Torres, Rubén; Pérez-Luque, Rosa; Escarmís, Cristina; Domingo, Esteban; Verdaguer, NuriaArtículo
Structure_Ferrer_et_al_JorViro_2010.pdf.jpg14-abr-2010Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to RibavirinFerrer-Orta, Cristina; Sierra, Macarena; Agudo Torres, Rubén; De la Higuera, Ignacio; Arias, Armando; Pérez-Luque, Rosa; Escarmís, Cristina; Domingo, Esteban; Verdaguer, NuriaArtículo
Topology_Ojosnegros_et_al_BMC_2008.pdf.jpg17-jul-2008Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selectionOjosnegros, Samuel; Agudo Torres, Rubén; Sierra, Macarena; Briones, Carlos; Sierra, Saleta; González-López, Claudia; Domingo, Esteban; Cristina, JuanArtículo