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Título : Role of MicroRNAs in human osteosarcoma : future perspectives
Autor : Llobat Bordes, Lola.
Gourbault, Olivia.
Materias: Osteosarcoma - Treatment.Huesos - Cáncer - Tratamiento.Tumor markers.Bones - Cancer - Treatment.Marcadores tumorales.Osteosarcoma - Tratamiento.
Fecha de publicación : 23-abr-2021
Editorial : MDPI
Citación : Llobat, L. & Gourbault, O. (2021). Role of MicroRNAs in human osteosarcoma: future perspectives. Biomedicines, vol. 9, i. 5 (23 apr.), art. 463. DOI: https://doi.org/10.3390/biomedicines9050463
Resumen : Osteosarcoma (OS) is a rare form of cancer with high death rate but is one of the most frequent forms of bone cancer in children and adolescents. MiRNAs are small endogenous RNAs that regulate gene expression post-transcriptionally. The discovery of miRNAs could allow us to obtain an earlier diagnosis, predict prognosis and chemoresistance, and lead to the discovery of new treatments in different types of tumors, including OS. Despite the fact that there is currently only one clinical trial being carried out on a single miRNA for solid tumors, it is very probable that the number of clinical trials including miRNAs as prognostic and diagnostic biomarkers, as well as potential therapeutic targets, will increase in the near future. This review summarizes the different miRNAs related to OS and their possible therapeutic application.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2227-9059/9/5/463
Este artículo pertenece al número especial "MicroRNAs, tRNA fragments, and circular RNAs: pivotal regulators of gene expression and their roles in human diseases".
URI : http://hdl.handle.net/10637/12890
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2227-9059 (Electrónico).
Aparece en las colecciones: Dpto. Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos

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