Intrinsic and environmental basis of aging: a narrative review

dc.centroUniversidad Cardenal Herrera-CEU
dc.contributor.authorNavarro, Carla
dc.contributor.authorSalazar, Juan
dc.contributor.authorDíaz, María P.
dc.contributor.authorChacín González, Maricarmen
dc.contributor.authorSanteliz, Raquel
dc.contributor.authorVera, Ivana
dc.contributor.authorD'Marco Gascón, Luis Gerardo
dc.contributor.otherProducción Científica UCH 2023
dc.contributor.otherUCH. Departamento de Medicina y Cirugía
dc.date.accessioned2024-09-16T08:19:51Z
dc.date.available2024-09-16T08:19:51Z
dc.date.issued2023-08
dc.description.abstractLongevity has been a topic of interest since the beginnings of humanity, yet its aetiology and precise mechanisms remain to be elucidated. Aging is currently viewed as a physiological phenomenon characterized by the gradual degeneration of organic physiology and morphology due to the passage of time where both external and internal stimuli intervene. The influence of intrinsic factors, such as progressive telomere shortening, genome instability due to mutation buildup, the direct or indirect actions of age-related genes, and marked changes in epigenetic, metabolic, and mitochondrial patterns constitute a big part of its underlying endogenous mechanisms. On the other hand, several psychosocial and demographic factors, such as diet, physical activity, smoking, and drinking habits, may have an even more significant impact on shaping the aging process. Consequentially, implementing dietary and exercise patterns has been proposed as the most viable alternative strategy for attenuating the most typical degenerative aging changes, thus increasing the likelihood of prolonging lifespan and achieving successful aging.es_ES
dc.identifier.citationNavarro, C., Salazar, J., Díaz, M.P., Chacin, M., Santeliz, R., Vera, I., D Marco, L., Parra, H., Bernal, M.C., Castro, A., Escalona, D., García-Pacheco, H. & Bermúdez, V. (2023). Intrinsic and environmental basis of aging: a narrative review. Heliyon, vol. 9, i. 8 (aug.), art. e18239. DOI: https://doi.org/10.1016/j.heliyon.2023.e18239es_ES
dc.identifier.doihttps://doi.org/10.1016/j.heliyon.2023.e18239
dc.identifier.issn2405-8440 (Electrónico)
dc.identifier.urihttp://hdl.handle.net/10637/16171
dc.language.isoenes_ES
dc.publisherElsevieres_ES
dc.relation.ispartofHeliyon, vol. 9, i. 8 (aug.)
dc.rightsopen access
dc.rights.cchttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subjectEnvejecimientoes_ES
dc.subjectAgeinges_ES
dc.subjectEnfermedad de la pieles_ES
dc.subjectSkin diseaseses_ES
dc.subjectTelomerasaes_ES
dc.subjectTelomerasees_ES
dc.subjectObesidades_ES
dc.subjectObesityes_ES
dc.titleIntrinsic and environmental basis of aging: a narrative reviewes_ES
dc.typeArtículoes_ES
dspace.entity.typePublicationes

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