Galán de Mera, Antonio

Plants belonging to the genus Taraxacum are considered a nutritious food, being consumed raw or cooked. Additionally, these plants have long been used in folk medicine due to their choleretic, diuretic, antitumor, antioxidant, antiinflammatory, and hepatoprotective properties. This genus, with its complex taxonomy, includes several species that are difficult to distinguish. Its traditional use must be related not only to T. officinale F.H. Wigg., the most studied species, but also to others. The aim of this work is to compare five different common South European species of Taraxacum (T. obovatum (Willd.) DC., T. marginellum H. Lindb., T. hispanicum H. Lindb., T. lambinonii Soest and T. lacistrum Sahlin), in order to find differences between antioxidant and cytotoxic activities among them. Dissimilarities between species in LC/MS patterns, in in vitro and intracellular antioxidant activity and also in the cytotoxicity assay were found. T. marginellum was the most efficient extract reducing intracellular ROS levels although in in vitro assays, T. obovatum was the best free radical scavenger. A relevant cytotoxic effect was found in T. lacistrum extract over HeLa and HepG2 cell lines.

Catalpa bignonioides Walt. (Bignoniaceae) is a species that belongs to a tropical family but has been introduced in many countries as ornamental. Although this plant is consumed by indigenous cultures of South America for medical uses, experimental studies of the biological properties of Catalpa bignonioides are lacking. The aim of this work was to study the biological activity of crude extracts from either pods, seeds or leaves of Catalpa bignonioides which were collected in Spain. Ethyl ether, butanolic and aqueous fractions of the pod extract were also prepared and studied. We have examined the antimicrobial activity against five bacteria and one yeast, the cytotoxic activity against HepG2 cells and the anti-inflammatory and antinociceptive effects in rodents. A preliminary phytochemical analysis of the extracts and fractions was also conducted. Results showed no antimicrobial or antitumoral effects, but prominent anti-inflammatory and antinociceptive actions of the extracts. These last activities may be a result of the presence of either of saponins, sterols or phenols, mainly found in the leaves and pods of the plants.

According to the research developed by André Leroi-Gourhan in 1964, entitled “Gesture and speech”, the evolution of human beings during Prehistory was linked to the search for work e ciency. As time passed, man designed increasingly complex tools whose production implied a decreasing amount of energy. The aim of the present research was to determine if this evolution, which occurred in parallel to the sedentary process, also a ected architecture, specifically if it can be detected on traditional dwellings, particularly in those built by the Native American Indians during the pre-Columbian period. Due to their great diversity, since both nomad and sedentary models can be found among them, and to the available information about their morphology and technical characteristics, these models o er a unique opportunity to study the consequences of this process for architecture. In order to achieve it, an alternative parameter that can be determined for any type of building was designed. It allows us to establish the amount of energy an envelope is equal to. The results obtained suggest that the e ciency of the dwellings decreased as this process went forward, but this pattern changed in its last step, when agriculture appeared and permanent settlements started to be built. Besides, statistical graphs were used in order to show graphically the relationship between it, the climate, the morphology of the dwellings and their technical characteristics.