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Molecular and serological studies on potential SARS-CoV-2 infection among 43 lemurs under human care-evidence for past infection in at least one individual


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Título : Molecular and serological studies on potential SARS-CoV-2 infection among 43 lemurs under human care-evidence for past infection in at least one individual
Autor : Musoles Cuenca, Beatriz
Aguiló Gisbert, Jordi
Lorenzo Bermejo, Teresa
Canales, Rocío
Ballester Llobell, Beatriz
Romani Cremaschi, Umberto
Martínez Valverde, Rosa
Maiques Fernández, Elisa
Marteles, Diana
Rueda, Pablo
Rubio, Vicente
Villanueva Saz, Sergio
Rubio Guerri, Consuelo
Materias: SARS-CoV-2 (Virus)LemursLemures
Editorial : MDPI
Citación : Musoles-Cuenca, B., Aguiló-Gisbert, J., Lorenzo-Bermejo, T., Canales, R., Ballester, B., Romani-Cremaschi, U., Martínez-Valverde, R., Maiques, E., Marteles, D., Rueda, P., Rubio, V., Villanueva-Saz, S. & Rubio-Guerri, C. (2023). Molecular and serological studies on potential SARS-CoV-2 infection among 43 lemurs under human care-evidence for past infection in at least one individual. Animals, vol. 14, i. 1, art. 140 (31 dec.). DOI: https://doi.org/10.3390/ani14010140
Resumen : In the setting of the recent COVID-19 pandemic, transmission of SARS-CoV-2 to animals has been reported in both domestic and wild animals and is a matter of concern. Given the genetic and functional similarities to humans, non-human primates merit particular attention. In the case of lemurs, generally considered endangered, they are believed to be susceptible to SARS-CoV-2 infection. We have conducted a study for evidence of SARS-CoV-2 infection among the 43 lemurs of Mundomar, a zoological park in Benidorm, Spain. They belong to two endangered lemur species, 23 black-and-white ruffed lemurs (Varecia variegata) and 20 ring-tailed lemurs (Lemur catta). Health assessments conducted in 2022 and 2023 included molecular analyses for SARS-CoV-2 RNA of oral and rectal swabs using two different RT-qPCR assays, always with negative results for SARS-CoV-2 in all animals. The assessment also included serological testing for antibodies against the receptor-binding domain (RBD) of the spike protein (S) of SARS-CoV-2, which again yielded negative results in all animals except one black-and-white ruffed lemur, supporting prior infection of that animal with SARS-CoV-2. Our data, while not indicating a high susceptibility of lemurs to SARS-CoV-2 infection, show that they can be infected, adding to the existing information body on potential ways for SARS-CoV-2 virus spreading in zoos, highlighting the need for animal surveillance for the virus.
URI : http://hdl.handle.net/10637/15088
Derechos: Open Access
https://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2076-2615 (Electrónico)
Fecha de publicación : 31-dic-2023
Centro : Universidad Cardenal Herrera-CEU
Aparece en las colecciones: Dpto. Ciencias Biomédicas





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