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Obesity and Gray Matter Volume Assessed by Neuroimaging : A Systematic Review

Título : Obesity and Gray Matter Volume Assessed by Neuroimaging : A Systematic Review
Autor : Fernández-Andújar, Marina
Morales García, Ester
García Casares, Natalia
Materias: Obesidad.Trastornos de la cognición.Demencia.Obesitat.Trastorns de la cognició.Demència.
Editorial : [Switzerland] : MDPI Multidisciplinary Digital Publishing Institute, 2021
Citación : Fernández-Andújar, Marina. Morales-García, Ester. García-Casares, Natalia. (2021). "Obesity and Gray Matter Volume Assessed by Neuroimaging : A Systematic Review". Brain Sciences, Volume 11, Number 8, Article 999 (August 2021), p. 1-24. ISSN-e 2076-3425. DOI: 10.3390/brainsci11080999
Resumen : Obesity has become a major public and individual health problem due to its high worldwide prevalence and its relation with comorbid conditions. According to previous studies, obesity is related to an increased risk of cognitive impairment and dementia. This systematic review aims to further examine the present state of the art about the association between obesity and gray matter volume (GMV) as assessed by magnetic resonance imaging (MRI). A search was conducted in Pubmed, SCOPUS and Cochrane of those studies released before 1 February 2021 including MRIs to assess the GMVs in obese participants. From this search, 1420 results were obtained, and 34 publications were finally included. Obesity was mainly measured by the body mass index, although other common types of evaluations were used (e.g., waist circumference, waist-to-hip ratio and plasma leptin levels). The selected neuroimaging analysis methods were voxel-based morphometry (VBM) and cortical thickness (CT), finding 21 and 13 publications, respectively. There were 30 cross-sectional and 2 prospective longitudinal studies, and 2 articles had both cross-sectional and longitudinal designs. Most studies showed a negative association between obesity and GMV. This would have important public health implications, as obesity prevention could avoid a potential risk of GMV reductions, cognitive impairment and dementia.
Descripción : En: Brain Sciences, Volume 11, Number 8, Article 999 (August 2021), p. 1-24. ISSN-e 2076-3425. DOI : 10.3390 / brainsci11080999
1 recurs en línia (p. 1-24)
URI : http://hdl.handle.net/10637/13880
ISSN : 2076-3425 (Electrónico)
Fecha de publicación : 19-sep-2022
Centro : Universitat Abat Oliba CEU
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